Reactome | GlyK166-ATG10 [cytosol]

GlyK166-ATG10 [cytosol]

Stable Identifier

R-HSA-5683572

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin-like-conjugating enzyme ATG10 ecNumber6.3.2.-/ecNumber, ATG10_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H0Y0 ATG10

Gene Names

ATG10, APG10L, PP12616

Chain

chain:1-220

Reference Genes

BioGPS Gene:83734 ATG10

COSMIC (genes):ATG10 ATG10

CTD Gene:83734 ATG10

dbSNP Gene:83734 ATG10

ENSEMBL:ENSG00000152348 ATG10

ENSEMBL:ENSG00000152348.16 ATG10

HGNC:20315 ATG10

KEGG Gene (Homo sapiens):83734 ATG10

Monarch:83734 ATG10

NCBI Gene:83734 ATG10

OMIM:610800 ATG10

UCSC:Q9H0Y0 ATG10

Reference Transcript

Other Identifiers

11734244_a_at

11740158_x_at

1570523_PM_s_at

1570523_s_at

16986847

207774_PM_at

207774_at

223677_PM_at

223677_at

243477_PM_at

243477_at

2818213

2818214

2818215

2818216

2818217

2818225

2818231

2818232

2818233

2818234

2818243

2818257

2818259

2818261

2818262

2818263

2818264

75668_at

78181_r_at

80875_i_at

80877_r_at

8106709

83734

83873_at

A_14_P114183

A_14_P118320

A_14_P119300

A_23_P92824

A_24_P370471

A_33_P3418400

GE580626

GO:0003824

GO:0005515

GO:0005737

GO:0005829

GO:0006497

GO:0006914

GO:0006983

GO:0008152

GO:0015031

GO:0016236

GO:0016740

GO:0019777

GO:0019787

GO:0023052

GO:0031401

GO:0032446

GO:0036211

GO:0140096

HMNXSV003042850

Hs.132303.0.A1_3p_at

Hs2.436246.1.S1_3p_x_at

ILMN_1748968

ILMN_2206098

PH_hs_0019535

g12053318_3p_at

g13489080_3p_at

Participates

as a component of

ATG12:GlyK166-ATG10 [cytosol] (Homo sapiens)

Other forms of this molecule

ATG10 [cytosol]

Inferred To

Atg10 [cytosol] (Mus musculus)

Atg10 [cytosol] (Rattus norvegicus)

GlyK166-ATG10 [cytosol] (Danio rerio)

GlyK166-ATG10 [cytosol] (Gallus gallus)

ATG10 [cytosol] (Bos taurus)

ATG10 [cytosol] (Sus scrofa)

Modified Residues

Name

N6-glycyl-L-lysine at 166

Coordinate

166

PsiMod Name

N6-glycyl-L-lysine

PsiMod Definition

A protein modification that effectively crosslinks an L-lysine residue and a glycine residue by an isopeptide bond to form N6-glycyl-L-lysine.

Cross References

RefSeq

NP_113670.1, NP_001124500.1, XP_005248668.1, XP_005248667.1

OpenTargets

ENSG00000152348

GeneCards

Q9H0Y0

HPA

ENSG00000152348-ATG10

Ensembl

ENST00000355178, ENST00000458350, ENST00000513443, ENSP00000425182, ENSG00000152348, ENSP00000282185, ENSP00000404938, ENST00000282185, ENSP00000347309

PRO

Q9H0Y0

Pharos - Targets

Q9H0Y0

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O94817 ATG12	2	ATG12 [phagocytic vesicle membrane] (R-HSA-5205625) ATG12 [cytosol] (R-HSA-936011)	0.564	2
UniProt:O75400-2 PRPF40A			0.556	3
UniProt:Q9Y3C5 RNF11			0.556	3
UniProt:O60260-5 PRKN			0.556	3
UniProt:Q8NI60 COQ8A			0.556	3
UniProt:P62826 RAN	2	RAN [nucleoplasm] (R-HSA-165528) RAN [cytosol] (R-HSA-165540)	0.556	3
UniProt:P37840 SNCA	5	SNCA A30P [cytosol] (R-HSA-5658569) SNCA [extracellular region] (R-HSA-976954) Ub-SNCA [cytosol] (R-HSA-5660754) p-S129-SNCA [cytosol] (R-HSA-9836432) SNCA [cytosol] (R-HSA-5658500)	0.556	3
UniProt:O00291 HIP1	7	HIP1(1-719)insL-ALK(1059-1620) fusion [cytosol] (R-HSA-9711952) HIP1(1-1019)-ALK(1058-1620) [cytosol] (R-HSA-9711970) HIP1(1-963)-ALK(1058-1620) fusion [cytosol] (R-HSA-9711972) HIP1(1-719)insL-p-7Y-ALK(1059-1620) fusion [cytosol] (R-HSA-9711965) HIP1(1-1019)-p-7Y-ALK(1058-1620) [cytosol] (R-HSA-9711956) HIP1(1-963)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9711975) HIP1 [cytosol] (R-HSA-8868153)	0.556	3
UniProt:Q9H1Y0 ATG5	3	ATG5 [phagocytic vesicle membrane] (R-HSA-5205636) GlyK130-ATG5 [cytosol] (R-HSA-5683582) ATG5 [cytosol] (R-HSA-936010)	0.556	5
UniProt:P13473-2 P134732			0.556	3
UniProt:P54253 ATX1			0.556	6
UniProt:P62879 GNB2	4	GNB2 [cytosol] (R-HSA-6814421) Partially folded GNB2 [cytosol] (R-HSA-8850536) Unfolded GNB2 [cytosol] (R-HSA-6814202) GNB2 [plasma membrane] (R-HSA-164335)	0.556	3
UniProt:P55212 CASP6	5	CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:O60333-2 KIF1B			0.556	3
UniProt:O95352 ATG7	14	ATG7 [secretory granule lumen] (R-HSA-6801316) ATG7 [extracellular region] (R-HSA-6806451) ATG7 [ficolin-1-rich granule lumen] (R-HSA-6801293) ATG7(1-693)-BRAF(381-766) fusion [cytosol] (R-HSA-6802272) ATG7(1-693)-p-BRAF(381-766) fusion [cytosol] (R-HSA-6802517) CysO572-ATG7-MAP1LC3B [cytosol] (R-HSA-9820410) CysO572-ATG7-GARABAPL2 [cytosol] (R-HSA-9820413) CysO572-ATG7-GARABAP [cytosol] (R-HSA-9820417) CysO572-ATG7-GARABAPL1 [cytosol] (R-HSA-9820406) CysO572-ATG7-MAP1LC3C [cytosol] (R-HSA-9820407) CysO572-ATG7-MAP1LC3A [cytosol] (R-HSA-9820421) CysO572-ATG7-GARABAPL3 [cytosol] (R-HSA-9820420) CysO572-ATG7 [cytosol] (R-HSA-5683584) ATG7 [cytosol] (R-HSA-947867)	0.527	2

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