Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyze Data
Species Comparison
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site map
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TRAPPC4 [cytosol]
Stable Identifier
R-HSA-5683764
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SBDN, CGI-104, HSPC172, PTD009, TRAPP1, TRAPP2, TRAPP3, TRAPP core
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPII-mediated vesicle transport (Homo sapiens)
COPII coat binds TRAPPCII and RAB1:GDP (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
Nucleotide exchange on RAB1 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
TRAPPC complexes exchange GTP for GDP on RAB1 (Homo sapiens)
TRAPPCs [cytosol] (Homo sapiens)
TRAPPCII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
TRAPPCIII [cytosol] (Homo sapiens)
TRAPPC4 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y296 TRAPPC4
Gene Names
TRAPPC4, SBDN, CGI-104, HSPC172, PTD009
Chain
chain:1-219
Reference Genes
BioGPS Gene:51399 TRAPPC4
COSMIC (genes):TRAPPC4 TRAPPC4
CTD Gene:51399 TRAPPC4
dbSNP Gene:51399 TRAPPC4
ENSEMBL:ENSG00000196655 TRAPPC4
ENSEMBL:ENSG00000280495 TRAPPC4
HGNC:19943 TRAPPC4
KEGG Gene (Homo sapiens):51399 TRAPPC4
Monarch:51399 TRAPPC4
NCBI Gene:51399 TRAPPC4
OMIM:610971 TRAPPC4
UCSC:Q9Y296 TRAPPC4
Reference Transcript
RefSeq:NM_001318494.1 TRAPPC4
RefSeq:NM_001318490.1 TRAPPC4
RefSeq:NM_001318489.1 TRAPPC4
RefSeq:NM_016146.5 TRAPPC4
RefSeq:NM_001318488.1 TRAPPC4
RefSeq:NM_001318492.1 TRAPPC4
RefSeq:NM_001318486.1 TRAPPC4
Other Identifiers
0002940592
11749400_a_at
16732088
217958_at
217959_s_at
2J3T
2JSN
2ZMV
3351777
3351778
3351779
3351782
3351784
3351788
3351789
3351790
3351793
39752
41371
51399
7894041
7944375
91724_at
A_14_P122802
A_14_P134701
A_23_P127613
AAD34099
AAD44494
AAF21897
AAF29135
AAH10866
AF078862
AF105025
AF151862
AF161520
AK290520
AK297422
AP003392
BAF83209
BAG59853
BC010866
CCDS81633
CCDS8407
CH471065
E9PKS9
E9PN70
E9PQE8
EAW67430
ENSG00000196655
ENSG00000280495
ENSP00000405033
ENSP00000436005
ENSP00000486496
ENSP00000487467
ENST00000434101
ENST00000434101.6
ENST00000533632
ENST00000533632.5
ENST00000629243
ENST00000629713
EntrezGene:51399
EntrezGene:TRAPPC4
G3V1A0
G5EA23
g7706666_3p_at
GE82084
GO:0000139
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005794
GO:0005795
GO:0005829
GO:0006810
GO:0006888
GO:0008021
GO:0008150
GO:0016192
GO:0016358
GO:0017112
GO:0019899
GO:0022607
GO:0030008
GO:0030154
GO:0030425
GO:0031410
GO:0032991
GO:0043226
GO:0045202
GO:0048208
GO:0048856
GO:0061024
GO:0065003
HGNC:19943
HPA039752
HPA041371
ILMN_1814650
IPR007233
IPR011012
J3KP27
MIM:610971
NM_001318486
NM_001318489
NM_001318492
NM_016146
NP_001305415
NP_001305418
NP_001305421
NP_057230
PF04099
PH_hs_0014423
SM01399
TC11001080.hg
TRAPPC4
TRAPPC4-202
TRAPPC4-214
TRAPPC4-221
TRAPPC4-222
UPI0000052E23
UPI00017A7669
Participant Of
hasComponent
TRAPPCII [cytosol]
TRAPPCIII [cytosol]
Other forms of this molecule
TRAPPC4 [plasma membrane]
Inferred To
TRAPPC4 [cytosol] (Bos taurus)
TRAPPC4 [cytosol] (Caenorhabditis elegans)
TRAPPC4 [cytosol] (Canis familiaris)
TRAPPC4 [cytosol] (Danio rerio)
TRAPPC4 [cytosol] (Dictyostelium discoideum)
TRAPPC4 [cytosol] (Drosophila melanogaster)
TRAPPC4 [cytosol] (Gallus gallus)
TRAPPC4 [cytosol] (Mus musculus)
TRAPPC4 [cytosol] (Plasmodium falciparum)
TRAPPC4 [cytosol] (Rattus norvegicus)
TRAPPC4 [cytosol] (Saccharomyces cerevisiae)
TRAPPC4 [cytosol] (Schizosaccharomyces pombe)
TRAPPC4 [cytosol] (Sus scrofa)
TRAPPC4 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
NP_001305419.1
,
NP_001305417.1
,
NP_001305421.1
,
NP_001305418.1
,
NP_001305415.1
,
NP_057230.1
,
NP_001305423.1
OpenTargets
ENSG00000196655
GeneCards
Q9Y296
PRO
Q9Y296
PDB
2JSN
,
2J3T
,
2ZMV
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96QF0 RAB3IP
1
RAB3IP [cytosol]
(R-HSA-5617610)
0.735
5
UniProt:P28482 MAPK1
8
MAPK1 [azurophil granule lumen]
(R-HSA-6799225)
MAPK1 [endoplasmic reticulum lumen]
(R-HSA-9636293)
MAPK1 [extracellular region]
(R-HSA-6806250)
MAPK1 [ficolin-1-rich granule lumen]
(R-HSA-6800964)
MAPK1 [cytosol]
(R-HSA-59282)
MAPK1 [nucleoplasm]
(R-HSA-199960)
p-T185,Y187-MAPK1 [nucleoplasm]
(R-HSA-112354)
p-T185,Y187-MAPK1 [cytosol]
(R-HSA-109853)
0.581
3
UniProt:O75865 TRAPPC6A
1
TRAPPC6A [cytosol]
(R-HSA-5685733)
0.544
2
UniProt:Q9BZR8 BCL2L14
1
BCL2L14 [cytosol]
(R-HSA-6791317)
0.527
2
UniProt:Q9Y5R8 TRAPPC1
3
TRAPPC1 [azurophil granule lumen]
(R-HSA-6799360)
TRAPPC1 [extracellular region]
(R-HSA-6806180)
TRAPPC1 [cytosol]
(R-HSA-5683750)
0.508
2
© 2019
Reactome