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pro-SFTPB [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-5683841
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Pulmonary surfactant-associated protein B, PSPB_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
SFTPB gene produces pro-SFTPB protein (Homo sapiens)
pro-SFTPB [endoplasmic reticulum membrane] (Homo sapiens)
pro-SFTPB translocates from ER membrane to multivesicle body (Homo sapiens)
pro-SFTPB [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P07988 SFTPB
Gene Names
SFTPB, SFTP3
Chain
signal peptide:1-24, propeptide:25-200, chain:201-279, propeptide:280-381
Reference Genes
BioGPS Gene:6439 SFTPB
COSMIC (genes):SFTPB SFTPB
CTD Gene:6439 SFTPB
dbSNP Gene:6439 SFTPB
ENSEMBL:ENSG00000168878 SFTPB
ENSEMBL_homo_sapiens_GENE:ENSG00000168878.19 SFTPB
HGNC:10801 SFTPB
KEGG Gene (Homo sapiens):6439 SFTPB
Monarch:6439 SFTPB
NCBI Gene:6439 SFTPB
OMIM:178640 SFTPB
UCSC:P07988 SFTPB
Reference Transcript
RefSeq:NM_198843.2 SFTPB
RefSeq:NM_000542.3 SFTPB
Other Identifiers
11734773_x_at
11734774_s_at
11734775_x_at
11747224_s_at
11749911_x_at
11755508_x_at
16899739
209810_PM_at
209810_at
213936_PM_x_at
213936_x_at
214354_PM_x_at
214354_x_at
2562436
2562437
2562438
2562439
2562440
2562441
2562442
2562443
2562444
2562445
2562446
2562453
2562454
2562456
2562458
2562459
2562460
2562461
2562463
2562464
2562466
2562467
2562468
2562469
33383_f_at
37004_PM_at
37004_at
6439
8053467
A_23_P17044
A_33_P3275873
A_33_P3275878
GE86029
GO:0005515
GO:0005576
GO:0005737
GO:0005764
GO:0005768
GO:0005771
GO:0005773
GO:0005783
GO:0005789
GO:0006629
GO:0006665
GO:0007585
GO:0009887
GO:0031410
GO:0042599
GO:0043226
GO:0045334
GO:0048856
GO:0097208
GO:0097486
HMNXSV003022016
HMNXSV003052841
Hs.264330.0.S1_3p_x_at
Hs.264330.1.S1_3p_s_at
ILMN_1727017
ILMN_2359835
M24461_at
PH_hs_0026815
PH_hs_0034353
TC02002046.hg
TC02004378.hg
g190673_3p_at
g190673_3p_s_at
Participates
as an output of
SFTPB gene produces pro-SFTPB protein (Homo sapiens)
as an input of
pro-SFTPB translocates from ER membrane to multivesicle body (Homo sapiens)
Other forms of this molecule
SFTPB Q45Kfs*8 [endoplasmic reticulum membrane]
SFTPB P121Efs*95 [endoplasmic reticulum membrane]
SFTPB [extracellular region]
SFTPB [clathrin-coated endocytic vesicle]
SFTPB [lamellar body]
pro-SFTPB [multivesicular body lumen]
SFTPB(201-279) [multivesicular body lumen]
SFTPB(280-381) [multivesicular body lumen]
SFTPB(25-200) [multivesicular body lumen]
Inferred To
spp-10 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of pro-SFTPB [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of pro-SFTPB [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Sftpb [endoplasmic reticulum membrane]
(Mus musculus)
Sftpb [endoplasmic reticulum membrane]
(Rattus norvegicus)
pro-SFTPB [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
pro-SFTPB [endoplasmic reticulum membrane]
(Gallus gallus)
spp-8 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
SFTPB [endoplasmic reticulum membrane]
(Bos taurus)
SFTPB [endoplasmic reticulum membrane]
(Canis familiaris)
SFTPB [endoplasmic reticulum membrane]
(Sus scrofa)
Sap-r [endoplasmic reticulum membrane]
(Drosophila melanogaster)
sapA [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_942140.2
,
NP_000533.3
OpenTargets
ENSG00000168878
HPA
ENSG00000168878-SFTPB
GeneCards
P07988
Ensembl
ENSP00000386346
,
ENSG00000168878
,
ENST00000393822
,
ENSP00000377409
,
ENST00000519937
,
ENST00000409383
,
ENSP00000428719
PRO
P07988
Pharos - Targets
P07988
Orphanet
15278
PDB
1RG3
,
1DFW
,
1SSZ
,
1KMR
,
2DWF
,
2M0H
,
1RG4
,
2JOU
,
2M1T
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q6FHY5 Q6FHY5
0.556
3
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