Reactome: A Curated Pathway Database

CHEK1 phosphorylates RAD51

Stable Identifier
R-HSA-5685230
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Activated CHEK1 phosphorylates RAD51 on threonine residue T309, which is necessary for RAD51 association with chromatin (Sorensen et al. 2005).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm] p-S317,S345-CHEK1 [nucleoplasm] protein serine/threonine kinase activity (0004674)
Orthologous Events