Reactome: A Curated Pathway Database

SLAMF6 binds SLAMF6

Stable Identifier
R-HSA-5685604
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Members of the signaling lymphocytic-activation molecule (SLAM) family, are all encoded in the SLAM locus, and are mostly homotypic self-associating receptors expressed by cells of hemopoietic origin (Veillette et al. 2006). SLAMF6 (also called as NTB-A) is a homophilic receptor that stimulates cytotoxicity in natural killer (NK) cells, regulates bactericidal activities in neutrophils, and potentiates T helper 2 (Th2) responses (Cao et al. 2006).

Literature References
Participants
Participant Of
Orthologous Events