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PALM-C100-CKAP4 [plasma membrane]
Stable Identifier
R-HSA-5686280
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Cytoskeleton-associated protein 4, CKAP4_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q9P0L0 VAPA
Expand all
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
PALM-C100-CKAP4 binds SFTPAs (Homo sapiens)
PALM-C100-CKAP4 [plasma membrane] (Homo sapiens)
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Homo sapiens)
PALM-C100-CKAP4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q07065 CKAP4
Gene Names
CKAP4
Chain
chain:1-602
Reference Genes
BioGPS Gene:10970 CKAP4
COSMIC (genes):CKAP4 CKAP4
CTD Gene:10970 CKAP4
dbSNP Gene:10970 CKAP4
ENSEMBL:ENSG00000136026 CKAP4
ENSEMBL_homo_sapiens_GENE:ENSG00000136026.14 CKAP4
HGNC:16991 CKAP4
KEGG Gene (Homo sapiens):10970 CKAP4
Monarch:10970 CKAP4
NCBI Gene:10970 CKAP4
OMIM:618595 CKAP4
UCSC:Q07065 CKAP4
Reference Transcript
RefSeq:NM_006825.3 CKAP4
Other Identifiers
10970
11726583_s_at
11746889_a_at
16769585
200998_PM_s_at
200998_s_at
200999_PM_s_at
200999_s_at
32529_at
3469686
3469688
3469689
3469690
3469691
3469692
3469693
3469694
3469704
3469705
3469706
3469707
3469708
3469709
3469710
3469711
7966035
A_23_P48056
GE59965
GO:0003723
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005773
GO:0005783
GO:0005788
GO:0005789
GO:0005791
GO:0005811
GO:0005856
GO:0005886
GO:0016020
GO:0031410
GO:0035577
GO:0035579
GO:0042599
GO:0043226
GO:0048471
GO:0070062
HMNXSV003030067
Hs.74368.0.A1_3p_a_at
PH_hs_0004243
TC12001917.hg
TC12003061.hg
TC12003062.hg
X69910_at
g5803112_3p_a_at
Participates
as an output of
ZDHHC2 transfers PALM from PALM-CoA to CKAP4 (Homo sapiens)
as a component of
PALM-C100-CKAP4:SFTPAs [plasma membrane] (Homo sapiens)
as an input of
PALM-C100-CKAP4 binds SFTPAs (Homo sapiens)
Other forms of this molecule
CKAP4 [endoplasmic reticulum lumen]
p-CKAP4 [endoplasmic reticulum lumen]
CKAP4 [azurophil granule membrane]
CKAP4 [plasma membrane]
CKAP4 [specific granule membrane]
PALM-C100-CKAP4 [lamellar body]
Inferred To
ckap4 [plasma membrane]
(Danio rerio)
ckap4 [plasma membrane]
(Xenopus tropicalis)
CKAP4 [plasma membrane]
(Bos taurus)
CKAP4 [plasma membrane]
(Canis familiaris)
CKAP4 [plasma membrane]
(Sus scrofa)
Ckap4 [plasma membrane]
(Mus musculus)
Ckap4 [plasma membrane]
(Rattus norvegicus)
PALM-C100-CKAP4 [plasma membrane]
(Gallus gallus)
Modified Residues
Name
S-palmitoyl-L-cysteine (palmitoyl group) at 100
Coordinate
100
Modification
palmitoyl group
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Cross References
RefSeq
NP_006816.2
OpenTargets
ENSG00000136026
HPA
ENSG00000136026-CKAP4
GeneCards
Q07065
Ensembl
ENSP00000367265
,
ENST00000378026
,
ENSG00000136026
PRO
Q07065
Pharos - Targets
Q07065
Interactors (20)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NVF7 FBX28
0.643
6
UniProt:P50876 RNF144A
1
RNF144A [endosome membrane]
(R-HSA-8938771)
0.589
2
UniProt:P27824 CANX
2
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.569
3
UniProt:Q92633 LPAR1
1
LPAR1 [plasma membrane]
(R-HSA-419354)
0.527
3
UniProt:O95274 LYPD3
2
cleaved GPI-LYPD3 [extracellular region]
(R-HSA-8941013)
GPI-LYPD3 [plasma membrane]
(R-HSA-8940752)
0.527
3
UniProt:Q7LGA3 HS2ST1
1
HS2ST1 [Golgi membrane]
(R-HSA-2076393)
0.527
3
UniProt:P30825 SLC7A1
1
SLC7A1 [plasma membrane]
(R-HSA-375771)
0.527
2
UniProt:Q9H8X2 IPPK
2
IPPK [cytosol]
(R-HSA-1604598)
IPPK [nucleoplasm]
(R-HSA-2023949)
0.527
2
UniProt:O75326 SEMA7A
1
SEMA7A [plasma membrane]
(R-HSA-198229)
0.527
2
UniProt:P08842 STS
3
STS [endoplasmic reticulum lumen]
(R-HSA-1614318)
OxA-STS [endoplasmic reticulum lumen]
(R-HSA-1614333)
OxA-STS [endoplasmic reticulum membrane]
(R-HSA-1606833)
0.527
2
UniProt:Q9UGM1 CHRNA9
1
CHRNA9 [plasma membrane]
(R-HSA-507827)
0.527
2
UniProt:Q9Y6Z7 COLEC10
1
COLEC10 [extracellular region]
(R-HSA-8852492)
0.527
2
UniProt:Q9P0L0 VAPA
4
VAPA [endoplasmic reticulum membrane]
(R-HSA-429677)
VAPA [azurophil granule membrane]
(R-HSA-6799364)
VAPA [plasma membrane]
(R-HSA-6806269)
VAPA [cytosol]
(R-HSA-9609920)
0.527
3
UniProt:Q9BZR6 RTN4R
1
RTN4R [plasma membrane]
(R-HSA-194479)
0.527
2
UniProt:P51888 PRELP
11
PRELP [lysosomal lumen]
(R-HSA-2105006)
KS(2)-PRELP [lysosomal lumen]
(R-HSA-2046286)
KS(2)-PRELP [extracellular region]
(R-HSA-2046162)
KS(2)-PRELP [Golgi lumen]
(R-HSA-2046160)
KS(1)-PRELP [Golgi lumen]
(R-HSA-2046258)
Keratan(4)-PRELP [Golgi lumen]
(R-HSA-2046276)
Keratan(3)-PRELP [Golgi lumen]
(R-HSA-2046159)
Keratan(2)-PRELP [Golgi lumen]
(R-HSA-2046219)
Keratan(1)-PRELP [Golgi lumen]
(R-HSA-2046292)
Gal-glycan PRELP [Golgi lumen]
(R-HSA-2046279)
N-glycan PRELP [Golgi lumen]
(R-HSA-2046156)
0.527
3
UniProt:O94766 B3GAT3
2
B3GAT3 R277Q [Golgi membrane]
(R-HSA-3621732)
B3GAT3 [Golgi membrane]
(R-HSA-1889987)
0.527
4
UniProt:Q13503 MED21
1
MED21 [nucleoplasm]
(R-HSA-212456)
0.527
2
UniProt:Q5BJH7 YIF1B
0.499
2
UniProt:P04578-PRO_0000038428 ENV
0.462
2
UniProt:P04578 env
7
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
ENV [viral envelope]
(R-HIV-173439)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
0.462
4
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