MYC binds to consensus sites in the MAPKAPK5 gene promoter as assessed by ChIP (Kress et al, 2011). Although not depicted here and not experimentally validated in this context, MYC likely binds the promoter in the context of a MYC:MAX heterodimer.
Kress, TR, Cannell, IG, Brenkman, AB, Samans, B, Gaestel, M, Roepman, P, Burgering, BM, Bushell, M, Rosenwald, A, Eilers, M
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