p-S215 FOXO3 binds MIR34B and C gene

Stable Identifier
R-HSA-5687095
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Phosphorylated FOXO3 binds to consensus sites in the promoter of MIR34B and C genes as assessed by ChIP, promoting expression of the microRNAs (Kress et al, 2011).

Literature References
PubMed ID Title Journal Year
21329882 The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis

Kress, TR, Cannell, IG, Brenkman, AB, Samans, B, Gaestel, M, Roepman, P, Burgering, BM, Bushell, M, Rosenwald, A, Eilers, M

Mol. Cell 2011
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