NCOA3 interacts with ETV4 (also known as PEA3) in a manner that depends on S857 phosphorylation (Long et al, 2012). ETV4 and NCOA3 coactivate expression of a number of MMP genes, which play roles in cell motility and invasiveness in a subset of lung carcinomas (Long et al, 2012; Qin et al, 2008; Yan et al, 2008).
Long, W, Foulds, CE, Qin, J, Qin, J, Liu, J, Ding, C, Lonard, DM, Solis, LM, Wistuba, II, Tsai, SY, Tsai, MJ, O'Malley, BW
Yan, J, Erdem, H, Li, R, Cai, Y, Ayala, G, Ittmann, M, Yu-Lee, LY, Tsai, SY, Tsai, MJ
Qin, L, Liao, L, Redmond, A, Young, L, Yuan, Y, Chen, H, O'Malley, BW, Xu, J
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