Reactome | POLL [nucleoplasm]

POLL [nucleoplasm]

Stable Identifier

R-HSA-5687352

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA polymerase lambda, DNA polymerase beta-2, Pol beta2, DNA polymerase kappa

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9UGP5 POLL

Gene Names

POLL

Chain

chain:1-575

Reference Genes

BioGPS Gene:27343 POLL

COSMIC (genes):POLL POLL

CTD Gene:27343 POLL

dbSNP Gene:27343 POLL

ENSEMBL:ENSG00000166169 POLL

HGNC:9184 POLL

KEGG Gene (Homo sapiens):27343 POLL

Monarch:27343 POLL

NCBI Gene:27343 POLL

OMIM:606343 POLL

UCSC:Q9UGP5 POLL

Reference Transcript

Other Identifiers

0001240672

11720777_x_at

11748194_a_at

11748769_a_at

11749030_x_at

11751320_a_at

11755961_x_at

16717706

221049_s_at

27343

3303878

3303879

3303880

3303881

3303882

3303884

3303885

3303887

3303890

3303891

3303893

3303894

3303896

3303897

3303900

3303901

3303903

3303904

3303905

3303906

57684_at

7935865

A_23_P97889

A_33_P3282669

A_33_P3326423

GE55220

GO:0000724

GO:0002376

GO:0003674

GO:0003677

GO:0003887

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0006259

GO:0006260

GO:0006281

GO:0006287

GO:0006289

GO:0006303

GO:0006950

GO:0006974

GO:0008150

GO:0009058

GO:0016446

GO:0016740

GO:0016779

GO:0016829

GO:0034061

GO:0034641

GO:0043167

GO:0043226

GO:0046872

GO:0048856

GO:0051575

GO:0071897

ILMN_1745787

PH_hs_0029169

TC10001607.hg

TC10002807.hg

g7019490_3p_a_at

Participant Of

hasMember

POLL,POLM [nucleoplasm]

Inferred To

poll [nucleoplasm] (Danio rerio)

POLL [nucleoplasm] (Canis familiaris)

POLL [nucleoplasm] (Gallus gallus)

POLL [nucleoplasm] (Sus scrofa)

POLL [nucleoplasm] (Xenopus tropicalis)

Poll [nucleoplasm] (Mus musculus)

Poll [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001167556.1, XP_011537953.1, NP_001295311.1, NP_037406.1, XP_006717840.1, NP_001167555.1

OpenTargets

ENSG00000166169

IntEnz

2.7.7.7

GeneCards

Q9UGP5

ZINC - Substances

DPOLL_HUMAN

HPA

ENSG00000166169-POLL

Ensembl

ENSP00000359188, ENST00000370162, ENST00000299206, ENSG00000166169, ENSP00000485885, ENST00000628479, ENSP00000359181, ENST00000370169, ENSP00000299206

ZINC target

Q9UGP5

PRO

Q9UGP5

HMDB Protein

HMDBP00955

PDB

4K4H, 3UQ0, 5IIM, 4K4G, 3UPQ, 5CJ7, 3PML, 3MDA, 5CR0, 5IIN, 3MGI, 2JW5, 2BCQ, 4K4I, 4X5V, 3HX0, 5IIL, 3MDC, 3PMN, 3UQ2, 3C5G, 3HWT, 3PNC, 4FO6, 1NZP, 4XRH, 3MGH, 1RZT, 5CB1, 2GWS, 3HW8, 5CWR, 5DDY, 2PFQ, 3C5F, 5CP2, 2PFP, 5DDM, 5IIK, 5CA7, 5CHG, 4XUS, 5DKW, 4XQ8, 5III, 1XSL, 2BCS, 5IIJ, 2BCR, 5W4G, 5IIO, 1XSP, 2PFO, 2BCV, 1XSN, 2BCU, 2PFN, 4XA5

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14191 WRN	2	WRN [nucleoplasm] (R-HSA-67387) SUMO1-K356,K496,K898-WRN [nucleoplasm] (R-HSA-4568904)	0.508	2
UniProt:P27694 RPA1	2	RPA1 [nucleoplasm] (R-HSA-68461) SUMO2,3-K449,K577-RPA1 [nucleoplasm] (R-HSA-4551644)	0.508	2
UniProt:Q08945 SSRP1	1	SSRP1 [nucleoplasm] (R-HSA-65105)	0.508	2
UniProt:Q9Y5B9 SUPT16H	1	SUPT16H [nucleoplasm] (R-HSA-112415)	0.508	2