Reactome | BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-5688142

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Locations in the PathwayBrowser for interactor UniProt:P61266 STX1B

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External Reference Information

External Reference

UniProt:O15155 BET1

Gene Names

BET1

Chain

chain:1-118

Reference Genes

BioGPS Gene:10282 BET1

COSMIC (genes):BET1 BET1

CTD Gene:10282 BET1

dbSNP Gene:10282 BET1

ENSEMBL:ENSG00000105829 BET1

HGNC:14562 BET1

KEGG Gene (Homo sapiens):10282 BET1

Monarch:10282 BET1

NCBI Gene:10282 BET1

OMIM:605456 BET1

UCSC:O15155 BET1

Reference Transcript

Other Identifiers

0003520091

10282

11719815_at

11719816_s_at

11719817_x_at

11754136_x_at

202710_at

3061667

3061668

3061669

3061670

3061671

3061672

3061673

3061675

3061676

3061682

33434_at

33435_r_at

8141024

AF007551_at

A_23_P59700

GE54088

GO:0000138

GO:0000139

GO:0003674

GO:0005484

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0006810

GO:0006888

GO:0008150

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0022607

GO:0030133

GO:0030173

GO:0030674

GO:0031201

GO:0031410

GO:0032991

GO:0033116

GO:0043226

GO:0048208

GO:0048280

GO:0061024

GO:0065003

ILMN_1684042

PH_hs_0002026

g12654162_3p_at

Participant Of

output

NSF ATPase activity dissociates cis-SNARE

hasComponent

BET1:GOSR2:STX5:SCFD1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

hasMember

ERGIC-to-cis-Golgi cargo [endoplasmic reticulum-Golgi intermediate compartment membrane]

Other forms of this molecule

BET1 [Golgi membrane]

BET1 [transport vesicle]

Inferred To

sft1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Schizosaccharomyces pombe)

BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Dictyostelium discoideum)

BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)

BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Saccharomyces cerevisiae)

BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)

Bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

Bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

Ghost homologue of BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

Ghost homologue of BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Plasmodium falciparum)

Homologues of BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Schizosaccharomyces pombe)

bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Danio rerio)

bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Schizosaccharomyces pombe)

bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Xenopus tropicalis)

nbet-1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001304668.1, NP_005859.1

OpenTargets

ENSG00000105829

HPA

ENSG00000105829-BET1

GeneCards

O15155

Ensembl

ENSP00000222547, ENST00000222547, ENST00000433727, ENSP00000391228, ENSG00000105829

PRO

O15155

PDB

3EGX

Interactors (60)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12846 STX4	4	STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [plasma membrane] (R-HSA-181519) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.718	6
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [Golgi membrane] (R-HSA-6807755) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800)	0.696	5
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.597	3
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.597	3
UniProt:Q99675 CGRF1			0.556	3
UniProt:P11912 CD79A	2	CD79A [plasma membrane] (R-HSA-197154) p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539)	0.556	3
UniProt:Q96KR6 F210B			0.556	3
UniProt:Q9H115 NAPB	1	NAPB [cytosol] (R-HSA-5688553)	0.556	3
UniProt:Q53FP2 TM35A			0.556	3
UniProt:Q8TBP5 F174A			0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:P49447 CY561			0.556	3
UniProt:Q8WWH4 ASZ1	1	ASZ1 [cytosol] (R-HSA-5603069)	0.556	3
UniProt:P07307-3 ASGR2			0.556	3
UniProt:Q9Y320 TMX2			0.556	3
UniProt:P48051 KCNJ6	1	KCNJ6 [plasma membrane] (R-HSA-975242)	0.556	3
UniProt:Q4KMG9 TM52B			0.556	3
UniProt:Q9BUF7-2 Q9BUF72			0.556	3
UniProt:O14880 MGST3	1	MGST3 [endoplasmic reticulum membrane] (R-HSA-176053)	0.556	3
UniProt:Q9H6H4 REEP4	1	REEP4 [endoplasmic reticulum membrane] (R-HSA-8939764)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:O14684 PTGES	1	PTGES [endoplasmic reticulum membrane] (R-HSA-2142717)	0.556	3
UniProt:Q9GZR5 ELOVL4	1	ELOVL4 [endoplasmic reticulum membrane] (R-HSA-548705)	0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q96HE8 TMM80			0.556	3
UniProt:Q68DC2 ANKS6			0.556	3
UniProt:Q9BXS9-3 SLC26A6			0.556	3
UniProt:Q9GZY8-5 MFF			0.556	3
UniProt:P43360 MAGA6			0.556	3
UniProt:Q8WWF3 SSMM1			0.556	3
UniProt:P32856-2 STX2			0.556	3
UniProt:Q8N6L0 KASH5			0.556	3
UniProt:Q6UWN5 LYPD5	2	GPI-LYPD5 [plasma membrane] (R-HSA-8940779) cleaved GPI-LYPD5 [extracellular region] (R-HSA-8941140)	0.556	3
UniProt:Q8TBB6 S7A14			0.556	3
UniProt:Q9BQA9 CYBC1			0.556	3
UniProt:P61266 STX1B	3	STX1B(?-288) [plasma membrane] (R-HSA-5246519) STX1B(1-?) [cytosol] (R-HSA-5246520) STX1B [plasma membrane] (R-HSA-181479)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:P29274 ADORA2A	2	ADORA2A [plasma membrane] (R-HSA-418934) ADORA2A [Golgi membrane] (R-HSA-187668)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:Q16623 STX1A	6	STX1A [plasma membrane] (R-HSA-6794231) STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:Q8IUN9 CLEC10A	1	CLEC10A [plasma membrane] (R-HSA-1472863)	0.556	3
UniProt:Q8N5K1 CISD2			0.556	3
UniProt:Q8N6Q1 TMC5A			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q96Q45-2 TMEM237			0.556	3
UniProt:P04233-2 CD74			0.556	3
UniProt:O95471 CLDN7	2	CLDN7 [plasma membrane] (R-HSA-420004) CLDN7 [cell junction] (R-HSA-421241)	0.556	3
UniProt:Q8N6Y0 USBP1			0.508	2
UniProt:Q96AJ9 VTI1A	2	VTI1A [Golgi membrane] (R-HSA-6811035) VTI1A [trans-Golgi network membrane] (R-HSA-6813927)	0.462	2
UniProt:O15027 SEC16A	1	SEC16A [cytosol] (R-HSA-5685728)	0.462	2
UniProt:O15498 YKT6	5	PalmC-YKT6 [ER to Golgi transport vesicle membrane] (R-HSA-5688557) PalmC-YKT6 [endoplasmic reticulum membrane] (R-HSA-5688145) PalmC-YKT6 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688558) PalmC-YKT6 [transport vesicle] (R-HSA-6808794) PalmC-YKT6 [Golgi membrane] (R-HSA-6808792)	0.462	2
UniProt:O15400 STX7			0.462	2
UniProt:Q99747 NAPG	1	NAPG [cytosol] (R-HSA-5688555)	0.462	2
UniProt:O95249 GOSR1	2	GOSR1 [Golgi membrane] (R-HSA-6807753) GOSR1 [transport vesicle] (R-HSA-6784834)	0.462	2
UniProt:P46459 NSF	1	NSF [cytosol] (R-HSA-264471)	0.462	2
UniProt:Q8WVM8 SCFD1	1	SCFD1 [cytosol] (R-HSA-5688147)	0.462	2
UniProt:Q13190 STX5	5	STX5 [endoplasmic reticulum membrane] (R-HSA-5689474) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838) STX5 [cytosol] (R-HSA-9613991)	0.462	2
UniProt:O00161 SNAP23	5	SNAP23 [phagocytic vesicle membrane] (R-HSA-8863966) p-S95-SNAP23 [phagocytic vesicle membrane] (R-HSA-8863923) SNAP23 [tertiary granule membrane] (R-HSA-6806141) SNAP23 [plasma membrane] (R-HSA-376345) SNAP23 [specific granule membrane] (R-HSA-6806157)	0.462	2

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