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TRAF7 [cytosol]
Stable Identifier
R-HSA-5688973
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase TRAF7 ecNumber6.3.2.-/ecNumber, TRAF7_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
TRAF7 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6Q0C0 TRAF7
Gene Names
TRAF7, RFWD1, RNF119
Chain
chain:1-670
Reference Genes
BioGPS Gene:84231 TRAF7
COSMIC (genes):TRAF7 TRAF7
CTD Gene:84231 TRAF7
dbSNP Gene:84231 TRAF7
ENSEMBL:ENSG00000131653 TRAF7
ENSEMBL_homo_sapiens_GENE:ENSG00000131653.14 TRAF7
HGNC:20456 TRAF7
KEGG Gene (Homo sapiens):84231 TRAF7
Monarch:84231 TRAF7
NCBI Gene:84231 TRAF7
OMIM:606692 TRAF7
UCSC:Q6Q0C0 TRAF7
Reference Transcript
RefSeq:NM_032271.2 TRAF7
Other Identifiers
11743349_a_at
11754528_s_at
16815001
223029_PM_s_at
223029_s_at
223031_PM_s_at
223031_s_at
3644540
3644545
3644546
3644547
3644548
3644549
3644554
3644555
3644556
3644557
3644558
3644559
3644561
3644562
3644564
3644566
3644571
3644574
3644576
3644578
3644580
3644582
3644584
3644585
3644586
3644587
3644588
3644589
3644590
45250_at
45251_g_at
65739_at
7992529
84231
A_14_P118746
A_23_P206474
A_24_P53150
GE83356
GO:0000027
GO:0000151
GO:0003824
GO:0004842
GO:0005515
GO:0005634
GO:0005730
GO:0005737
GO:0005886
GO:0006915
GO:0007219
GO:0008270
GO:0012501
GO:0016567
GO:0016740
GO:0023052
GO:0030163
GO:0031410
GO:0035519
GO:0036211
GO:0042254
GO:0043226
GO:0043231
GO:0043410
GO:0043525
GO:0046872
GO:0061630
GO:0065003
GO:0070372
GO:0140096
GO:2000060
GO:2001235
HMNXSV003047740
Hs.181077.0.S1_3p_a_at
ILMN_1654408
ILMN_2405991
PH_hs_0023801
TC16000063.hg
g12053336_3p_a_at
Participates
as a candidate of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
FBXW7 [cytosol]
(Gallus gallus)
TRAF7 [cytosol]
(Canis familiaris)
TRAF7 [cytosol]
(Sus scrofa)
Traf7 [cytosol]
(Mus musculus)
Traf7 [cytosol]
(Rattus norvegicus)
sel-10 [cytosol]
(Caenorhabditis elegans)
traf7 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_115647.2
OpenTargets
ENSG00000131653
IntEnz
2.3.2.27
HPA
ENSG00000131653-TRAF7
GeneCards
Q6Q0C0
Ensembl
ENSG00000131653
,
ENSP00000318944
,
ENSP00000515903
,
ENST00000326181
,
ENST00000704452
PRO
Q6Q0C0
Pharos - Targets
Q6Q0C0
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