Reactome | TRIM41 [cytosol]

TRIM41 [cytosol]

Stable Identifier

R-HSA-5688975

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

E3 ubiquitin-protein ligase TRIM41 ecNumber6.3.2.-/ecNumber, TRI41_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8WV44 TRIM41

Gene Names

TRIM41, RINCK

Chain

chain:1-630

Reference Genes

BioGPS Gene:90933 TRIM41

COSMIC (genes):TRIM41 TRIM41

CTD Gene:90933 TRIM41

dbSNP Gene:90933 TRIM41

ENSEMBL:ENSG00000146063 TRIM41

ENSEMBL_homo_sapiens_GENE:ENSG00000146063.20 TRIM41

HGNC:19013 TRIM41

KEGG Gene (Homo sapiens):90933 TRIM41

Monarch:90933 TRIM41

NCBI Gene:90933 TRIM41

OMIM:610530 TRIM41

UCSC:Q8WV44 TRIM41

Reference Transcript

Other Identifiers

11726971_a_at

11749621_a_at

11749622_x_at

11756426_x_at

16993611

226445_PM_s_at

226445_s_at

2845044

2845045

2845046

2845047

2845048

2845049

2845050

2845053

2845055

2845058

2845059

2845061

2845062

2845063

2845064

2845065

2845066

2845067

2845069

55604_at

77794_at

79801_at

8110649

90933

A_23_P167521

A_24_P252020

A_33_P3216316

A_33_P3354434

GE56759

GO:0002376

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0006513

GO:0008270

GO:0016567

GO:0016604

GO:0016740

GO:0023052

GO:0036211

GO:0042802

GO:0043226

GO:0046872

GO:0051607

GO:0060340

GO:0061630

GO:0071222

GO:0071225

GO:0098542

GO:0140096

HMNXSV003049057

Hs.332612.0.A1_3p_s_at

ILMN_1729495

ILMN_1813027

PH_hs_0016727

TC05001083.hg

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)

Inferred To

LOC100485429 [cytosol] (Xenopus tropicalis)

trim108 [cytosol] (Danio rerio)

Homologues of TRIM41 [cytosol] (Danio rerio)

Trim41 [cytosol] (Rattus norvegicus)

trim109 [cytosol] (Danio rerio)

TRIM41 [cytosol] (Bos taurus)

TRIM41 [cytosol] (Caenorhabditis elegans)

TRIM41 [cytosol] (Canis familiaris)

TRIM41 [cytosol] (Gallus gallus)

TRIM41 [cytosol] (Mus musculus)

TRIM41 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_963921.1, NP_291027.3

OpenTargets

ENSG00000146063

HPA

ENSG00000146063-TRIM41

GeneCards

Q8WV44

Ensembl

ENST00000315073, ENST00000351937, ENSP00000336749, ENSG00000146063, ENSP00000320869

PRO

Q8WV44

Pharos - Targets

Q8WV44

PDB

2EGM

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.831	8
UniProt:O43639 NCK2	1	NCK2 [cytosol] (R-HSA-204885)	0.718	8
UniProt:Q96EZ8 MCRS1	1	MCRS1 [nucleoplasm] (R-HSA-3321849)	0.556	3
UniProt:O43463 SUV39H1	1	SUV39H1 [nucleoplasm] (R-HSA-427517)	0.556	3
UniProt:Q8N0S2 SYCE1	1	SYCE1 [nucleoplasm] (R-HSA-912456)	0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:P55081 MFAP1	1	MFAP1 [nucleoplasm] (R-HSA-2396419)	0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	5
UniProt:Q9GZV8 PRDM14	1	PRDM14 [nucleoplasm] (R-HSA-1112608)	0.556	3
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:P26045 PTPN3	3	PTPN3 [plasma membrane] (R-HSA-5490317) p-S459 PTPN3 [cytosol] (R-HSA-8868111) PTPN3 [cytosol] (R-HSA-8867650)	0.556	3
UniProt:Q05513 PRKCZ	5	p-T410,T563-PRKCZ [cytosol] (R-HSA-5218698) PRKCZ [cytosol] (R-HSA-58218) PRKCZ [cell junction] (R-HSA-2134483) p-T410-PRKCZ [cytosol] (R-HSA-437181) pS, p-T410-PRKCZ [cytosol] (R-HSA-9632824)	0.527	2
UniProt:P03466 NP	6	NP [Golgi membrane] (R-FLU-195740) NP [plasma membrane] (R-FLU-195752) NP [extracellular region] (R-FLU-169251) NP [endosome lumen] (R-FLU-189141) NP [cytosol] (R-FLU-188848) NP [nucleoplasm] (R-FLU-188832)	0.499	5