Reactome | STX5 [endoplasmic reticulum membrane]

STX5 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-5689474

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        Loss of SAR1B GTPase (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        Cargo concentration in the ER (Homo sapiens)
        
        Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC4C,D bind GOSR2 and STX5 (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)

Vesicle-mediated transport (Homo sapiens)

- Membrane Trafficking (Homo sapiens)
  - ER to Golgi Anterograde Transport (Homo sapiens)
    - COPII-mediated vesicle transport (Homo sapiens)
      - Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
      - Loss of SAR1B GTPase (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
      - SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
      - SEC31:SEC13 and v-SNARE recruitment (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
      - Vesicle budding (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
    - Cargo concentration in the ER (Homo sapiens)
      - Inner coat assembly and cargo binding (Homo sapiens)
        
        COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
      - SEC4C,D bind GOSR2 and STX5 (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        SEC23A:SEC24C,D:GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        GOSR2,STX5 [endoplasmic reticulum membrane] (Homo sapiens)
        
        STX5 [endoplasmic reticulum membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q13190 STX5

Gene Names

STX5, STX5A

Chain

chain:1-355

Reference Genes

BioGPS Gene:6811 STX5

COSMIC (genes):STX5 STX5

CTD Gene:6811 STX5

dbSNP Gene:6811 STX5

ENSEMBL:ENSG00000162236 STX5

HGNC:11440 STX5

KEGG Gene (Homo sapiens):6811 STX5

Monarch:6811 STX5

NCBI Gene:6811 STX5

OMIM:603189 STX5

UCSC:Q13190 STX5

Reference Transcript

Other Identifiers

0005910403

11717259_a_at

11748552_a_at

1358

16739588

203330_s_at

3376194

3376195

3376196

3376206

3376208

3376210

3376212

3376213

3376215

3376216

3376217

3376222

3376223

3376226

3EFO

40068_at

6811

7948864

A_23_P24755

AAC71078

AAH02645

AAH12137

AAV38452

AAV38453

AK313497

AP001160

BAG36279

BC002645

BC012137

BT019646

BT019647

BX537426

CAD97668

CCDS58140

CCDS8038

CCDS81578

E9PNU4

E9PP18

E9PRW9

ENSG00000162236

ENSP00000294179

ENSP00000367129

ENSP00000378182

ENST00000294179

ENST00000294179.7

ENST00000377897

ENST00000377897.8

ENST00000394690

ENST00000394690.5

EntrezGene:6811

EntrezGene:STX5

g4507292_3p_s_at

GE79529

GO:0000139

GO:0000149

GO:0003674

GO:0005484

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0006810

GO:0006886

GO:0006888

GO:0006906

GO:0008150

GO:0009056

GO:0012505

GO:0012507

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0022607

GO:0031201

GO:0031410

GO:0031982

GO:0032991

GO:0033116

GO:0034498

GO:0042147

GO:0043226

GO:0045296

GO:0045732

GO:0047485

GO:0048208

GO:0048278

GO:0048280

GO:0061024

GO:0065003

GO:0090166

GO:1903358

HGNC:11440

HPA001358

ILMN_1749345

ILMN_1777444

ILMN_1808860

IPR000727

IPR006012

IPR010989

IPR021538

MIM:603189

NM_001244666

NM_001330294

NM_003164

NP_001231595

NP_001317223

NP_003155

PF05739

PF11416

PH_hs_0019737

SM00397

STX5

STX5-201

STX5-202

STX5-203

TC11001881.hg

U26648

U26648_at

UPI0000136164

UPI00001FA9B0

UPI000037446E

XM_011545224

XP_011543526

Participant Of

hasMember

Other forms of this molecule

STX5 [Golgi membrane]

STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane]

STX5 [ER to Golgi transport vesicle membrane]

STX5 [cytosol]

Inferred To

syn5 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

syx-5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Stx5 [endoplasmic reticulum membrane] (Mus musculus)

Stx5 [endoplasmic reticulum membrane] (Rattus norvegicus)

sed5 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

stx5a [endoplasmic reticulum membrane] (Danio rerio)

STX5 [endoplasmic reticulum membrane] (Bos taurus)

STX5 [endoplasmic reticulum membrane] (Canis familiaris)

STX5 [endoplasmic reticulum membrane] (Plasmodium falciparum)

STX5 [endoplasmic reticulum membrane] (Sus scrofa)

SED5 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

stx5 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_003155.2, NP_001317223.1, NP_001231595.1

OpenTargets

ENSG00000162236

HPA

ENSG00000162236-STX5

GeneCards

Q13190

Ensembl

ENST00000394690, ENSG00000162236, ENSP00000378182, ENST00000377897, ENSP00000294179, ENST00000294179, ENSP00000367129

PRO

Q13190

PDB

3EFO

Interactors (33)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61764 STXBP1	2	STXBP1 [cytosol] (R-HSA-6794256) STXBP1 [plasma membrane] (R-HSA-2980862)	0.718	6
UniProt:Q12846 STX4	4	STX4 [phagocytic vesicle membrane] (R-HSA-2029044) STX4 [plasma membrane] (R-HSA-181519) STX4 [cytosol] (R-HSA-114505) p-STX4 [cytosol] (R-HSA-114681)	0.718	6
UniProt:Q8N6L0 KASH5			0.718	6
UniProt:Q9H115 NAPB	1	NAPB [cytosol] (R-HSA-5688553)	0.718	9
UniProt:O95183 VAMP5			0.666	4
IntAct:EBI-22326698 CCSB ORF ID			0.556	3
UniProt:Q4LEZ3 AARD			0.556	3
UniProt:Q8NBQ5 HSD17B11	1	HSD17B11 [cytosol] (R-HSA-5693370)	0.556	3
UniProt:O75410 TACC1			0.556	3
UniProt:P43360 MAGA6			0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:P32856-2 STX2			0.556	3
UniProt:Q494R4-2 CCDC153			0.556	3
UniProt:O95872 GPAN1			0.556	3
UniProt:Q9BUF7-2 Q9BUF72			0.556	3
UniProt:Q9H6H4 REEP4	1	REEP4 [endoplasmic reticulum membrane] (R-HSA-8939764)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:Q9UNK0 STX8			0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:Q86VR2 RETR3			0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:Q9HCJ2 LRC4C			0.556	3
UniProt:Q9ULD2-3 MTUS1			0.556	3
UniProt:P38932	1	VPS45 [endosome membrane] (R-SCE-1011607)	0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3
UniProt:Q86WV6 TMEM173	5	TMEM173 [endoplasmic reticulum membrane] (R-HSA-1834940) K63polyUb-STING [endoplasmic reticulum membrane] (R-HSA-3134805) K63polyUb-STING [cytoplasmic vesicle membrane] (R-HSA-3248021) TMEM173 [plasma membrane] (R-HSA-6804815) TMEM173 [secretory granule membrane] (R-HSA-6804798)	0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [Golgi membrane] (R-HSA-6807755) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800)	0.556	3
UniProt:Q68CJ9 CREB3L3	10	CREB3L3(1-?) [cytosol] (R-HSA-6784654) CREB3L3(1-?) [nucleoplasm] (R-HSA-6784629) CREB3L3 [endoplasmic reticulum membrane] (R-HSA-6784669) CREB3L3(?-461) [endoplasmic reticulum membrane] (R-HSA-6784710) CREB3L3 [Golgi membrane] (R-HSA-8874144) CREB3L3(365-461) [Golgi membrane] (R-HSA-8874130) CREB3L3(1-364) [Golgi membrane] (R-HSA-8874158) CREB3L3(1-323) [cytosol] (R-HSA-8874214) CREB3L3(1-323) [nucleoplasm] (R-HSA-8874217) CREB3L3(324-364) [Golgi membrane] (R-HSA-8874183)	0.556	3
UniProt:Q16623 STX1A	6	STX1A [plasma membrane] (R-HSA-6794231) STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:P54920 NAPA	1	NAPA [cytosol] (R-HSA-264469)	0.547	2
UniProt:O15155 BET1	3	BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142)	0.462	2

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