Reactome | BAP1 [nucleoplasm]

BAP1 [nucleoplasm]

Stable Identifier

R-HSA-5689665

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Ubiquitin carboxyl-terminal hydrolase BAP1 ecNumber3.4.19.12/ecNumber, BAP1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P85037

Expand all

External Reference Information

External Reference

UniProt:Q92560 BAP1

Gene Names

BAP1, KIAA0272, hucep-6

Chain

chain:1-729

Reference Genes

BioGPS Gene:8314 BAP1

COSMIC (genes):BAP1 BAP1

CTD Gene:8314 BAP1

dbSNP Gene:8314 BAP1

ENSEMBL:ENSG00000163930 BAP1

HGNC:950 BAP1

KEGG Gene (Homo sapiens):8314 BAP1

Monarch:8314 BAP1

NCBI Gene:8314 BAP1

OMIM:603089 BAP1

UCSC:Q92560 BAP1

Reference Transcript

RefSeq:NM_004656.3 BAP1

Other Identifiers

0004610059

11717028_a_at

11717029_a_at

11747830_a_at

1555735_a_at

16954770

201419_at

2676091

2676093

2676094

2676095

2676096

2676097

2676098

2676099

2676100

2676101

2676102

2676105

2676106

2676107

2676108

2676109

2676111

2676112

2676114

2676115

2676116

2676117

2676118

2676119

2676120

2676121

2676123

2676124

2676126

2676128

2676129

38682_at

8087885

8314

A_23_P259012

A_24_P302898

D87462_at

GE54395

GO:0001558

GO:0002376

GO:0003674

GO:0003682

GO:0004843

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006325

GO:0006464

GO:0006508

GO:0006511

GO:0006605

GO:0006810

GO:0006950

GO:0007005

GO:0007049

GO:0008150

GO:0008233

GO:0008234

GO:0008283

GO:0008285

GO:0009056

GO:0009058

GO:0010035

GO:0015031

GO:0016579

GO:0016787

GO:0018215

GO:0032991

GO:0034641

GO:0035517

GO:0035520

GO:0035522

GO:0040007

GO:0042592

GO:0043226

GO:0045892

GO:0050727

GO:0051276

GO:0051726

GO:0061519

GO:0071108

GO:1900015

GO:1903955

HMNXSV003014949

Hs2.106674.2.S1_3p_s_at

ILMN_1768363

PH_hs_0005935

TC03001453.hg

TC03002916.hg

g4757835_3p_at

Participates

as a component of

as an input of

Inferred To

uch2 [nucleoplasm] (Dictyostelium discoideum)

uch2 [nucleoplasm] (Schizosaccharomyces pombe)

bap1 [nucleoplasm] (Danio rerio)

bap1 [nucleoplasm] (Xenopus tropicalis)

calypso [nucleoplasm] (Drosophila melanogaster)

BAP1 [nucleoplasm] (Canis familiaris)

BAP1 [nucleoplasm] (Gallus gallus)

BAP1 [nucleoplasm] (Sus scrofa)

Bap1 [nucleoplasm] (Mus musculus)

Bap1 [nucleoplasm] (Rattus norvegicus)

UCH54 [nucleoplasm] (Plasmodium falciparum)

Cross References

RefSeq

NP_004647.1

Target Pathogen

5b354852be737e166372ebda

OpenTargets

ENSG00000163930

IntEnz

3.4.19.12

HPA

ENSG00000163930-BAP1

GeneCards

Q92560

Ensembl

ENSP00000417132, ENST00000460680, ENSG00000163930

PRO

Q92560

Orphanet

20738

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IXJ9 ASXL1	1	ASXL1 [nucleoplasm] (R-HSA-5689645)	0.793	7
UniProt:P51610 HCFC1	2	K48polyUb,K63polyUb-HCFC1 [nucleoplasm] (R-HSA-5690821) HCFC1 [nucleoplasm] (R-HSA-1592209)	0.688	4
UniProt:P85037 FOXK1	1	FOXK1 [nucleoplasm] (R-HSA-5689673)	0.669	3
UniProt:Q01167 FOXK2	1	FOXK2 [nucleoplasm] (R-HSA-5689655)	0.669	4
UniProt:Q14573 ITPR3	2	ITPR3 [endoplasmic reticulum membrane] (R-HSA-169690) ITPR3 [platelet dense tubular network membrane] (R-HSA-418283)	0.64	12
UniProt:Q8NB78 KDM1B	1	KDM1B [nucleoplasm] (R-HSA-5423072)	0.564	2
UniProt:Q76L83 ASXL2	1	ASXL2 [nucleoplasm] (R-HSA-5689629)	0.564	3
UniProt:O15294 OGT	2	OGT [cytosol] (R-HSA-9687814) OGT [nucleoplasm] (R-HSA-3321845)	0.564	3
UniProt:Q9C0C9 UBE2O	1	UBE2O [cytosol] (R-HSA-947641)	0.564	2
UniProt:P38398 BRCA1	27	SUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) SUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) BRCA1 C64R [nucleoplasm] (R-HSA-9700907) BRCA1 C61G [nucleoplasm] (R-HSA-9700890) BRCA1 C39Y [nucleoplasm] (R-HSA-9700938) BRCA1 H41R [nucleoplasm] (R-HSA-9700921) BRCA1 C24R [nucleoplasm] (R-HSA-9663198) BRCA1 H41A [nucleoplasm] (R-HSA-9700927) BRCA1 M18T [nucleoplasm] (R-HSA-9700911) BRCA1 C47G [nucleoplasm] (R-HSA-9700941) BRCA1 C64G [nucleoplasm] (R-HSA-9700899) BRCA1 C44F [nucleoplasm] (R-HSA-9700944) BRCA1 T37R [nucleoplasm] (R-HSA-9700934) BRCA1 C27A [nucleoplasm] (R-HSA-9700916) BRCA1 H41Q [nucleoplasm] (R-HSA-9700923) BRCA1 Q12Tfs5 [nucleoplasm] (R-HSA-9700953) BRCA1 E23Afs18 [nucleoplasm] (R-HSA-9700959) BRCA1 C61Y [nucleoplasm] (R-HSA-9700894) BRCA1 C24F [nucleoplasm] (R-HSA-9663206) BRCA1 E23Rfs18 [nucleoplasm] (R-HSA-9700960) BRCA1 E23Vfs17 [nucleoplasm] (R-HSA-9700967) p-S988,S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-5683800) K6PolyUb,p-S988,S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-9707298) BRCA1 [nucleoplasm] (R-HSA-50949) K6PolyUb-BRCA1 [nucleoplasm] (R-HSA-9701022) K6PolyUb,p-S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-9707290) p-S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-75234)	0.543	3
UniProt:Q9ULV8 CBLC			0.488	2
UniProt:P45973 CBX5	2	SUMO1-K84,K-CBX5 [nucleoplasm] (R-HSA-4615849) CBX5 [nucleoplasm] (R-HSA-994093)	0.488	2

Cite Us!