Reactome | CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-HSA-5689778

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

ERV14

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Asparagine N-linked glycosylation (Homo sapiens)
    - Transport to the Golgi and subsequent modification (Homo sapiens)
      - ER to Golgi Anterograde Transport (Homo sapiens)
        
        COPII-mediated vesicle transport (Homo sapiens)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Homo sapiens)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH1:TFGA,AREG precursors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)
        
        CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:O95406 CNIH1

Gene Names

CNIH1, CNIH, CNIL, UNQ155/PRO181

Chain

chain:1-144

Reference Genes

BioGPS Gene:10175 CNIH1

COSMIC (genes):CNIH1 CNIH1

CTD Gene:10175 CNIH1

dbSNP Gene:10175 CNIH1

ENSEMBL:ENSG00000100528 CNIH1

HGNC:19431 CNIH1

KEGG:hsa:10175 CNIH1

Monarch:10175 CNIH1

NCBI Gene:10175 CNIH1

OMIM:611287 CNIH1

UCSC:O95406 CNIH1

Reference Transcript

RefSeq:NM_005776.2 CNIH1

Other Identifiers

10175

11716360_a_at

16793149

201653_PM_at

201653_at

225553_PM_at

225553_at

32803_at

3565321

3565322

3565323

3565324

3565325

3565326

3565327

3565328

3565329

3565331

3565332

3565333

3565335

3565336

3565337

3565338

3565339

3565340

46130_at

7979250

82373_at

86764_at

A_23_P14473

A_24_P506726

GE62807

GE87993

GE87994

GO:0000139

GO:0002376

GO:0005515

GO:0005783

GO:0005789

GO:0005794

GO:0006888

GO:0006955

GO:0007165

GO:0012507

GO:0016020

GO:0016192

GO:0030134

GO:0031410

GO:0033116

GO:0043226

HMNXSV003014497

HMNXSV003034085

Hs.56847.0.S1_3p_at

ILMN_1758543

ILMN_1786532

ILMN_1903568

ILMN_2330112

PH_hs_0003677

PH_hs_0023562

TC14001149.hg

g5031638_3p_at

Participates

as a component of

CNIH1:TFGA,AREG precursors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Other forms of this molecule

CNIH1 [endoplasmic reticulum membrane]

CNIH1 [ER to Golgi transport vesicle membrane]

Inferred To

CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)

CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Gallus gallus)

CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)

Cnih1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Mus musculus)

Cnih1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000100528

ENSEMBL

ENSP00000216416, ENST00000216416

HPA

ENSG00000100528-CNIH1

PRO

O95406

Pharos - Targets

O95406

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BZL3 SMIM3			0.601	6
UniProt:Q13323 BIK			0.556	3
UniProt:P54219-3 P542193			0.556	3
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.556	3
UniProt:P19397 CD53	3	CD53 [tertiary granule membrane] (R-HSA-6804799) CD53 [plasma membrane] (R-HSA-6804817) CD53 [specific granule membrane] (R-HSA-6804793)	0.556	3
UniProt:P28335 HTR2C	1	HTR2C [plasma membrane] (R-HSA-390965)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:P00387 CYB5R3	3	CYB5R3(27-301) [azurophil granule lumen] (R-HSA-6799217) CYB5R3(27-301) [extracellular region] (R-HSA-6806205) MyrG-CYB5R3(2-301) [mitochondrial outer membrane] (R-HSA-198771)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:Q7Z7G2 CPLX4			0.556	3
UniProt:P34910-2 P349102			0.556	3
UniProt:Q96AG4 LRC59			0.556	3
UniProt:Q4KMG9 TM52B			0.556	3
UniProt:Q8IX19 MCEMP1	3	MCEMP1 [tertiary granule membrane] (R-HSA-6800975) MCEMP1 [plasma membrane] (R-HSA-6806288) MCEMP1 [specific granule membrane] (R-HSA-6799637)	0.556	3
UniProt:O95471 CLDN7	2	CLDN7 [plasma membrane] (R-HSA-420004) CLDN7 [cell junction] (R-HSA-421241)	0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q9NQQ7-3 Q9NQQ73			0.556	3
IntAct:EBI-22589183 CCSB ORF ID			0.556	3
UniProt:P35372-10 OPRM1			0.556	3
UniProt:A8MZ59 LEUTX	1	LEUTX [nucleoplasm] (R-HSA-9817277)	0.556	3
UniProt:Q8TDT2 GP152			0.556	3
UniProt:Q9GZY8-5 MFF			0.556	3
UniProt:Q9Y225-2 RNF24			0.556	3
UniProt:P11912 CD79A	2	p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539) CD79A [plasma membrane] (R-HSA-197154)	0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q96DD7 SHSA4			0.556	3
UniProt:A1A5C7-2 SLC22A23			0.556	3

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