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UCHL3 [cytosol]
Stable Identifier
R-HSA-5690773
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin carboxyl-terminal hydrolase isozyme L3, UCHL3_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
UCH proteinases (Homo sapiens)
UCHL1, UCHL3 cleave ubiquitin adducts (Homo sapiens)
UCHL1,UCHL3 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL1,UCHL3:Ub [cytosol] (Homo sapiens)
UCHL1,UCHL3 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL1,UCHL3:Ub-Lys [cytosol] (Homo sapiens)
UCHL1,UCHL3 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3, SENP8 cleave NEDD8 (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3,SENP8:NEDD8 [cytosol] (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3,SENP8:NEDD8(1-88) [cytosol] (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
Neddylation (Homo sapiens)
Release of mature NEDD8 (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3,SENP8:NEDD8 [cytosol] (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3, SENP8 cleave NEDD8 (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3,SENP8:NEDD8 [cytosol] (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3,SENP8:NEDD8(1-88) [cytosol] (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
UCHL3,USP7,USP9X cleaves RPS27A yielding ubiquitin (Homo sapiens)
UCHL3,USP7,USP9X [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
UCHL3,USP7,USP9X cleaves UBA52 yielding ubiquitin (Homo sapiens)
UCHL3,USP7,USP9X [cytosol] (Homo sapiens)
UCHL3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P15374 UCHL3
Gene Names
UCHL3
Chain
chain:1-230
Reference Genes
BioGPS Gene:7347 UCHL3
COSMIC (genes):UCHL3 UCHL3
CTD Gene:7347 UCHL3
dbSNP Gene:7347 UCHL3
ENSEMBL:ENSG00000118939 UCHL3
ENSEMBL_homo_sapiens_GENE:ENSG00000118939.19 UCHL3
HGNC:12515 UCHL3
KEGG Gene (Homo sapiens):7347 UCHL3
Monarch:7347 UCHL3
NCBI Gene:7347 UCHL3
OMIM:603090 UCHL3
UCSC:P15374 UCHL3
Reference Transcript
RefSeq:NM_001270952.1 UCHL3
RefSeq:NM_006002.4 UCHL3
Other Identifiers
11720232_at
16775421
204616_PM_at
204616_at
3494105
3494109
3494110
3494111
3494112
3494115
3494121
3494127
3494128
3494129
3494130
37244_at
7347
7969428
A_23_P76690
GO:0003824
GO:0004843
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006508
GO:0006511
GO:0008233
GO:0008234
GO:0016567
GO:0016579
GO:0016787
GO:0019784
GO:0030163
GO:0036211
GO:0043130
GO:0043226
GO:0043687
GO:0140096
HMNXSV003032007
M30496_at
PH_hs_0028985
TC13000285.hg
g5174740_3p_at
Participates
as a member of
UCHL1,UCHL3 [cytosol] (Homo sapiens)
UCHL3,USP7,USP9X [cytosol] (Homo sapiens)
UCHL3,SENP8 [cytosol] (Homo sapiens)
Inferred To
im:6908825 [cytosol]
(Danio rerio)
UCHL3 [cytosol]
(Bos taurus)
UCHL3 [cytosol]
(Canis familiaris)
UCHL3 [cytosol]
(Gallus gallus)
UCHL3 [cytosol]
(Plasmodium falciparum)
UCHL3 [cytosol]
(Sus scrofa)
ubh-3 [cytosol]
(Caenorhabditis elegans)
uch1 [cytosol]
(Dictyostelium discoideum)
uch1 [cytosol]
(Schizosaccharomyces pombe)
Uch [cytosol]
(Drosophila melanogaster)
YUH1 [cytosol]
(Saccharomyces cerevisiae)
Uchl3 [cytosol]
(Mus musculus)
Uchl3 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_005993.1
,
NP_001257881.1
Guide to Pharmacology - Targets
2427
OpenTargets
ENSG00000118939
IntEnz
3.4.19.12
GeneCards
P15374
HPA
ENSG00000118939-UCHL3
ZINC - Substances
UCHL3_HUMAN
ZINC target
P15374
Ensembl
ENSG00000118939
,
ENSP00000366819
,
ENST00000377595
PRO
P15374
Pharos - Targets
P15374
PDB
1UCH
,
1XD3
,
6QML
,
7YV4
,
6ISU
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