Reactome: A Curated Pathway Database

K48polyUb,K63polyUb-HCFC1

Stable Identifier
R-HSA-5690821
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Host cell factor 1, HCFC1_HUMAN, HCF1
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
HCFC1, HCF1, HFC1
Chain
initiator methionine:1, chain:2-1423, chain:2-1323, chain:2-1295, chain:2-1110, chain:2-1081, chain:2-1019, chain:1020-2035, chain:1082-2035, chain:1111-2035, chain:1296-2035, chain:1324-2035, chain:1424-2035
Reference Genes
Reference Transcript
Other Identifiers
 0007050075  11721129_at  11721130_at  11721131_x_at  11721132_at
 17115394  18312  202473_x_at  202474_s_at  3054
 37910_at  4026957  4026958  4026959  4026960
 4026961  4026962  4026963  4026965  4026967
 4026970  4026971  4026972  4026973  4026974
 4026975  4026976  4026977  4026978  4026979
 4026980  4026981  4026982  4026983  4026984
 4026985  4026986  4026987  4026988  4026990
 4026991  4026993  4026994  4026995  4026996
 4026998  4026999  4N39  4N3A  4N3B
 4N3C  8175947  A_23_P125771  AAH63435  BC063435
 CAA55790  CCDS44020  ENSG00000172534  ENSP00000309555  ENST00000310441
 EntrezGene:3054  g4885402_3p_a_at  GE62512  GO:0000122  GO:0000123
 GO:0000988  GO:0001071  GO:0001205  GO:0003674  GO:0003682
 GO:0003700  GO:0003713  GO:0005515  GO:0005575  GO:0005622
 GO:0005623  GO:0005634  GO:0005654  GO:0005671  GO:0005737
 GO:0006355  GO:0006366  GO:0006461  GO:0006464  GO:0007005
 GO:0007049  GO:0008134  GO:0008150  GO:0009058  GO:0010628
 GO:0016020  GO:0016032  GO:0016569  GO:0016579  GO:0016746
 GO:0019046  GO:0022607  GO:0030424  GO:0030425  GO:0033613
 GO:0034641  GO:0042802  GO:0043025  GO:0043226  GO:0043234
 GO:0043254  GO:0043981  GO:0043982  GO:0043984  GO:0043995
 GO:0043996  GO:0044403  GO:0045296  GO:0045787  GO:0045944
 GO:0046972  GO:0048188  GO:0050821  GO:0051276  GO:0065003
 GO:0070461  GO:0071339  GO:0071407  HCFC1  HCFC1-201
 HGNC:4839  HPA018312  Hs.83634  Hs.83634.0.S1_3p_a_at  ILMN_1732705
 IPR003961  IPR006652  IPR013783  IPR015915  IPR015916
 L20010  L20010_at  MIM:300019  MIM:309541  NM_005334
 NP_005325  PF01344  PF13415  PH_hs_0004770  SM00060
 TC0X001522.hg  U52112  uc004fjp.4  UPI0000142F1F  X79198
 XM_011531147  XM_011531148  XP_011529449  XP_011529450
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name Coordinate Modification PsiMod
ubiquitinylated lysine (K48-polyUb, K63-polyUb [nucleoplasm]) at 1807 1807 K48-polyUb, K63-polyUb [nucleoplasm]
ubiquitinylated lysine [MOD:01148] A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
UCSC human
GeneCards
DOCK Blaster
PRO
Orphanet
PDB
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.832 Q9NS37 ZHANG_HUMAN 10
0.764 O15294 OGT1_HUMAN 10
0.744 O43889 CREB3_HUMAN 5
0.708 P61964 WDR5_HUMAN 5
0.688 Q92560 BAP1_HUMAN 4
0.681 P08047 SP1_HUMAN 4
0.677 Q9UBL3 ASH2L_HUMAN 5
0.658 O43889-2 CREB3 4
0.605 Q96ST3 SIN3A_HUMAN 6
0.581 Q13105 ZBT17_HUMAN 9
0.564 Q9D1P2 KAT8_MOUSE 2
0.527 Q03164 KMT2A_HUMAN 2
0.508 Q06547-2 GABPB1 6
0.508 Q96EK4 THA11_HUMAN 2
0.499 O15047 SET1A_HUMAN 2
0.499 Q9H7L9 SDS3_HUMAN 2
0.499 Q06547 GABP1_HUMAN 3
0.499 Q06546 GABPA_HUMAN 2
0.499 P51610 HCFC1_HUMAN 2
0.499 Q13547 HDAC1_HUMAN 2
0.499 Q92769 HDAC2_HUMAN 2
0.462 Q9P0U4 CXXC1_HUMAN 2