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OX40 [plasma membrane]
Stable Identifier
R-HSA-5692210
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
TNFRSF4, Tumor necrosis factor receptor superfamily member 4, CD134
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
TNFR2 non-canonical NF-kB pathway (Homo sapiens)
TNFs bind their physiological receptors (Homo sapiens)
OX40L binds OX40 (Homo sapiens)
3xOX40:OX40L trimer [plasma membrane] (Homo sapiens)
OX40 [plasma membrane] (Homo sapiens)
OX40 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P43489 TNFRSF4
Gene Names
TNFRSF4, TXGP1L
Chain
signal peptide:1-28, chain:29-277
Reference Genes
BioGPS Gene:7293 TNFRSF4
COSMIC (genes):TNFRSF4 TNFRSF4
CTD Gene:7293 TNFRSF4
dbSNP Gene:7293 TNFRSF4
ENSEMBL:ENSG00000186827 TNFRSF4
ENSEMBL_homo_sapiens_GENE:ENSG00000186827.12 TNFRSF4
HGNC:11918 TNFRSF4
KEGG Gene (Homo sapiens):7293 TNFRSF4
Monarch:7293 TNFRSF4
NCBI Gene:7293 TNFRSF4
OMIM:600315 TNFRSF4
UCSC:P43489 TNFRSF4
Reference Transcript
RefSeq:XM_017002232.1 TNFRSF4
RefSeq:NM_003327.3 TNFRSF4
Other Identifiers
11727600_a_at
16680085
214228_3p_x_at
214228_PM_x_at
214228_x_at
2391173
2391174
2391176
2391178
2391180
2391182
2391185
2391186
2391187
34916_s_at
7293
7911413
A_32_P26092
A_33_P3286157
GO:0001618
GO:0002376
GO:0002639
GO:0005031
GO:0005515
GO:0005886
GO:0006351
GO:0006355
GO:0006954
GO:0006955
GO:0009897
GO:0009986
GO:0016020
GO:0023052
GO:0030890
GO:0033209
GO:0042098
GO:0043433
GO:0045892
GO:0046718
GO:0060089
Hs.129780.1.S1_3p_a_at
Hs.129780.1.S1_3p_at
Hs.129780.1.S1_3p_x_at
ILMN_1710204
ILMN_2112256
PH_hs_0007601
TC01002086.hg
Participates
as a component of
3xOX40:OX40L trimer [plasma membrane] (Homo sapiens)
as an input of
OX40L binds OX40 (Homo sapiens)
Inferred To
Tnfrsf4 [plasma membrane]
(Mus musculus)
Tnfrsf4 [plasma membrane]
(Rattus norvegicus)
OX40 [plasma membrane]
(Gallus gallus)
TNFRSF4 [plasma membrane]
(Bos taurus)
TNFRSF4 [plasma membrane]
(Canis familiaris)
TNFRSF4 [plasma membrane]
(Sus scrofa)
tnfrsf4 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_016857721.1
,
NP_003318.1
Guide to Pharmacology - Targets
1873
OpenTargets
ENSG00000186827
GeneCards
P43489
HPA
ENSG00000186827-TNFRSF4
Ensembl
ENSG00000186827
,
ENST00000379236
,
ENSP00000368538
PRO
P43489
Pharos - Targets
P43489
Orphanet
23272
PDB
6OGX
,
6OKM
,
7YK4
,
2HEV
,
2HEY
,
8AG1
,
6OKN
,
1D0A
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P23510 TNFSF4
1
TNFSF4 [plasma membrane]
(R-HSA-5666995)
0.558
2
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