Reactome: A Curated Pathway Database

ATP13A1 transports Mn2+ from cytosol to ER lumen

Stable Identifier
R-HSA-5692462
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Manganese-transporting ATPase 13A1 (ATP13A1) mediates the transport of manganese (Mn2+) into the endoplasmic reticulum. ATPase activity is required for cellular manganese homeostasis (Cohen et al. 2013).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
manganese-transporting ATPase activity of ATP13A1 [endoplasmic reticulum membrane] ATP13A1 [endoplasmic reticulum membrane] manganese-transporting ATPase activity (0015410)
Orthologous Events