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ATP13A2 transports cations from cytosol to lysosomal lumen

Stable Identifier
R-HSA-5692480
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The probable cation-transporting ATPase 13A2 (ATP13A2) is thought to play a role in intracellular cation homeostasis and the maintenance of neuronal integrity (Ramonet et al. 2012). Defects in ATP13A2 can cause Kufor-Rakeb syndrome (KRS; MIM:606693), a juvenile-onset Levodopa-responsive parkinsonism (Lai et al. 2012).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cation-transporting ATPase activity of ATP13A2 [lysosomal lumen]
Physical Entity
Activity
Orthologous Events