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CDC42EP2 [cytosol]
Stable Identifier
R-HSA-5692692
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
BORG1
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK6/MAPK4 signaling (Homo sapiens)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Homo sapiens)
CDC42EP2,3,5 [cytosol] (Homo sapiens)
CDC42EP2 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 binds effectors at the plasma membrane (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
CDC42EP2 [cytosol] (Homo sapiens)
CDC42:GTP:CDC42 effectors [plasma membrane] (Homo sapiens)
CDC42 effectors [cytosol] (Homo sapiens)
CDC42EP2 [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ binds effectors at the plasma membrane (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CDC42EP2 [cytosol] (Homo sapiens)
RHOQ:GTP:RHOQ effectors [plasma membrane] (Homo sapiens)
RHOQ effectors [cytosol] (Homo sapiens)
CDC42EP2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14613 CDC42EP2
Gene Names
CDC42EP2, BORG1, CEP2
Chain
initiator methionine:, chain:2-210
Reference Genes
BioGPS Gene:10435 CDC42EP2
COSMIC (genes):CDC42EP2 CDC42EP2
CTD Gene:10435 CDC42EP2
dbSNP Gene:10435 CDC42EP2
ENSEMBL:ENSG00000149798 CDC42EP2
ENSEMBL_homo_sapiens_GENE:ENSG00000149798.5 CDC42EP2
HGNC:16263 CDC42EP2
KEGG Gene (Homo sapiens):10435 CDC42EP2
Monarch:10435 CDC42EP2
NCBI Gene:10435 CDC42EP2
OMIM:606132 CDC42EP2
UCSC:O14613 CDC42EP2
Reference Transcript
RefSeq:NM_006779.3 CDC42EP2
RefSeq:XM_017017094.1 CDC42EP2
Other Identifiers
10435
11753904_a_at
16726825
209850_PM_s_at
209850_s_at
214014_PM_at
214014_at
3335071
3335072
3335075
3335076
3335077
3335078
3335079
3335081
41658_at
7941236
A_14_P124560
GE54039
GO:0001515
GO:0002376
GO:0005096
GO:0005515
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0007010
GO:0007015
GO:0007266
GO:0008360
GO:0012505
GO:0015630
GO:0016020
GO:0023052
GO:0030036
GO:0030838
GO:0031267
GO:0031274
GO:0031334
GO:0031410
GO:0043226
GO:0045335
GO:0048018
GO:0048856
GO:0065003
GO:0071346
GO:0098542
GO:0098772
HMNXSV003026253
ILMN_1652777
PH_hs_0001158
TC11000623.hg
g13529304_3p_a_at
Participates
as a candidate of
RHOQ effectors [cytosol] (Homo sapiens)
as a member of
CDC42 effectors [cytosol] (Homo sapiens)
CDC42EP2,3,5 [cytosol] (Homo sapiens)
Other forms of this molecule
p-CDC42EP2 [cytosol]
Inferred To
cdc42ep2 [cytosol]
(Danio rerio)
cdc42ep2 [cytosol]
(Xenopus tropicalis)
Cdc42ep2 [cytosol]
(Mus musculus)
Cdc42ep2 [cytosol]
(Rattus norvegicus)
CDC42EP2 [cytosol]
(Bos taurus)
CDC42EP2 [cytosol]
(Canis familiaris)
CDC42EP2 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_006770.1
,
XP_016872583.1
OpenTargets
ENSG00000149798
HPA
ENSG00000149798-CDC42EP2
GeneCards
O14613
Ensembl
ENST00000279249
,
ENSG00000149798
,
ENSP00000431660
,
ENSP00000279249
,
ENST00000533419
PRO
O14613
Pharos - Targets
O14613
HMDB Protein
HMDBP08319
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60953 CDC42
3
CDC42 [endoplasmic reticulum membrane]
(R-HSA-5672086)
CDC42 [cytosol]
(R-HSA-442630)
CDC42 [plasma membrane]
(R-HSA-449545)
0.83
10
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
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