MAPK6 binds CCND3

Stable Identifier
R-HSA-5692764
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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MAPK6 interacts with Cyclin D3 (CCND3) through its C-terminal extension, and this interaction is stabilized by overexpression of CDC14 phosphatase (Sun et al, 2006; Hansen et al, 2008). Although the physiological relevance of the interaction between MAPK6 and CCND3 is not known, both proteins regulate cell cycle entry and MAPK6 is stabilized during differentiation and upon inhibition of proliferation (Coulombe et al, 2003; Bartkova et al, 1998; Julien et al, 2003).

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Orthologous Events
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Created