MAPKAPK5 phosphorylates KALRN

Stable Identifier
R-HSA-5692768
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
MAPKAPK5 phosphorylates KALRN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

KALRN is phosphorylated in a MAPKAPK5-dependent manner (Brand et al, 2012).

Literature References
PubMed ID Title Journal Year
22508986 The extracellular signal-regulated kinase 3 (mitogen-activated protein kinase 6 [MAPK6])-MAPK-activated protein kinase 5 signaling complex regulates septin function and dendrite morphology

Brand, F, Schumacher, S, Kant, S, Menon, MB, Simon, R, Turgeon, B, Britsch, S, Meloche, S, Gaestel, M, Kotlyarov, A

Mol. Cell. Biol. 2012
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol]
Physical Entity
KALRN:p-S189 MAPK6:p-T182 MAPKAPK5 [cytosol]
Activity
protein serine/threonine kinase activity (0004674)
Orthologous Events
MAPKAPK5 phosphorylates KALRN (Bos taurus)
MAPKAPK5 phosphorylates KALRN (Canis familiaris)
MAPKAPK5 phosphorylates KALRN (Danio rerio)
MAPKAPK5 phosphorylates KALRN (Gallus gallus)
MAPKAPK5 phosphorylates KALRN (Mus musculus)
MAPKAPK5 phosphorylates KALRN (Rattus norvegicus)
MAPKAPK5 phosphorylates KALRN (Sus scrofa)
MAPKAPK5 phosphorylates KALRN (Xenopus tropicalis)
Authored
Meloche, S  (2015-05-12)
Reviewed
Mathien, S  (2015-05-12)
Meloche, S  (2015-05-12)
Soulez, M  (2015-05-12)
Created
Rothfels, K  (2015-05-13)
Cite Us!