TNFSF15 binds TNFRSF25

Stable Identifier
R-HSA-5693012
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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TNFRSF25 (also referred as DR3/TRAMP/LARD/WSL1) is a death-domain-containing tumor necrosis factor (TNF)-family receptor primarily expressed on T cells. It binds with TNFSF15 (TL1A), the TNF family ligand and induces T cell costimulation (Meylan et al. 2008).

Literature References
PubMed ID Title Journal Year
18571443 The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases

Meylan, F, Davidson, TS, Kahle, E, Kinder, M, Acharya, K, Jankovic, D, Bundoc, V, Hodges, M, Shevach, EM, Keane-Myers, A, Wang, EC, Siegel, RM

Immunity 2008
11911831 TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T cell costimulator

Migone, TS, Zhang, J, Luo, X, Zhuang, L, Chen, C, Hu, B, Hong, JS, Perry, JW, Chen, SF, Zhou, JX, Cho, YH, Ullrich, S, Kanakaraj, P, Carrell, J, Boyd, E, Olsen, HS, Hu, G, Pukac, L, Liu, D, Ni, J, Kim, S, Gentz, R, Feng, P, Moore, PA, Ruben, SM, Wei, P

Immunity 2002
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created