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CLCF1 [extracellular region]
Stable Identifier
R-HSA-5693175
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Cardiotrophin-like cytokine factor 1, CLCF1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-6 family signaling (Homo sapiens)
IL-6-type cytokine receptor ligand interactions (Homo sapiens)
CRLF1 binds CLCF1 (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
CRLF1:CLCF1 binds CNTRF (Homo sapiens)
CNTFR:CRLF1:CLCF1 [plasma membrane] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
LIFR:JAKs bind gp130:JAKs:CNTFR (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR [plasma membrane] (Homo sapiens)
CNTFR:CRLF1:CLCF1 [plasma membrane] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:gp130:JAKs:LIFR:JAKs [plasma membrane] (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR [plasma membrane] (Homo sapiens)
CNTFR:CRLF1:CLCF1 [plasma membrane] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
gp130:JAKs bind CNTFR (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR [plasma membrane] (Homo sapiens)
CNTFR:CRLF1:CLCF1 [plasma membrane] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR:IL6ST:JAK1, JAK2, (TYK2) [plasma membrane] (Homo sapiens)
CNTF:CNTFR,CRLF1:CLCF1:CNTFR [plasma membrane] (Homo sapiens)
CNTFR:CRLF1:CLCF1 [plasma membrane] (Homo sapiens)
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
CLCF1 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UBD9 CLCF1
Gene Names
CLCF1, BSF3, CLC, NNT1
Chain
signal peptide:1-27, chain:28-225
Reference Genes
BioGPS Gene:23529 CLCF1
COSMIC (genes):CLC CLCF1
COSMIC (genes):CLCF1 CLCF1
CTD Gene:23529 CLCF1
dbSNP Gene:23529 CLCF1
ENSEMBL:ENSG00000175505 CLCF1
HGNC:17412 CLCF1
KEGG:hsa:23529 CLCF1
Monarch:23529 CLCF1
NCBI Gene:23529 CLCF1
OMIM:607672 CLCF1
UCSC:Q9UBD9 CLCF1
Reference Transcript
RefSeq:NM_001166212.1 CLCF1
RefSeq:NM_013246.2 CLCF1
Participates
as an input of
CRLF1 binds CLCF1 (Homo sapiens)
as a component of
CRLF1:CLCF1 [extracellular region] (Homo sapiens)
Inferred To
Clcf1 [extracellular region]
(Mus musculus)
Clcf1 [extracellular region]
(Rattus norvegicus)
CLCF1 [extracellular region]
(Bos taurus)
CLCF1 [extracellular region]
(Canis familiaris)
CLCF1 [extracellular region]
(Gallus gallus)
CLCF1 [extracellular region]
(Sus scrofa)
Cross References
ENSEMBL
ENSG00000175505
,
ENST00000533438
,
ENST00000312438
,
ENSP00000309338
,
ENSP00000434122
OpenTargets
ENSG00000175505
GeneCards
CLCF1
HPA
ENSG00000175505-CLCF1
PRO
Q9UBD9
Pharos - Targets
Q9UBD9
GlyGen
Q9UBD9
Orphanet
CLCF1
PDB
8D7H
,
8D7R
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02649 APOE
10
APOE [extracellular region]
(R-HSA-174646)
APOE [endoplasmic reticulum lumen]
(R-HSA-6784908)
p-APOE [endoplasmic reticulum lumen]
(R-HSA-8956980)
APOE [endocytic vesicle lumen]
(R-HSA-3221641)
APOE-4 [extracellular region]
(R-HSA-9711070)
APOE [plasma membrane]
(R-HSA-174615)
APOE [clathrin-coated endocytic vesicle membrane]
(R-HSA-174651)
APOE [endosome membrane]
(R-HSA-174766)
APOE [endosome lumen]
(R-HSA-174804)
APOE [early endosome]
(R-HSA-2429687)
0.524
3
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