Ligation of DNA and formation of Holliday structures following repair synthesis

Stable Identifier
R-HSA-5693539
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Ligation of DNA and formation of Holliday structures following repair synthesis
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Ligation of the crossed-strand intermediate results in the formation of double Holliday junctions with two crossovers. In humans, the identity of the ligase activity involved in this process is not known (reviewed by Ciccia and Elledge 2010).
Literature References
PubMed ID Title Journal Year
20965415 The DNA damage response: making it safe to play with knives

Elledge, SJ, Ciccia, A

Mol. Cell 2010
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Orthologous Events
Ligation of DNA and formation of Holliday structures following repair synthesis (Bos taurus)
Ligation of DNA and formation of Holliday structures following repair synthesis (Canis familiaris)
Ligation of DNA and formation of Holliday structures following repair synthesis (Gallus gallus)
Ligation of DNA and formation of Holliday structures following repair synthesis (Mus musculus)
Ligation of DNA and formation of Holliday structures following repair synthesis (Rattus norvegicus)
Ligation of DNA and formation of Holliday structures following repair synthesis (Sus scrofa)
Authored
Matthews, L  (2003-08-11)
Reviewed
Borowiec, JA  (2015-06-12)
Created
Orlic-Milacic, M  (2015-05-16)
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