DNA double strand break (DSB) response involves sensing of DNA DSBs by the MRN complex which triggers ATM activation. ATM phosphorylates a number of proteins involved in DNA damage checkpoint signaling, as well as proteins directly involved in the repair of DNA DSBs. For a recent review, please refer to Ciccia and Elledge, 2010.

• DNA Double Strand Break Response (Arabidopsis thaliana)
• DNA Double Strand Break Response (Bos taurus)
• DNA Double Strand Break Response (Caenorhabditis elegans)
• DNA Double Strand Break Response (Canis familiaris)
• DNA Double Strand Break Response (Danio rerio)
• DNA Double Strand Break Response (Dictyostelium discoideum)
• DNA Double Strand Break Response (Drosophila melanogaster)
• DNA Double Strand Break Response (Gallus gallus)
• DNA Double Strand Break Response (Mus musculus)
• DNA Double Strand Break Response (Oryza sativa)
• DNA Double Strand Break Response (Plasmodium falciparum)
• DNA Double Strand Break Response (Rattus norvegicus)
• DNA Double Strand Break Response (Saccharomyces cerevisiae)
• DNA Double Strand Break Response (Schizosaccharomyces pombe)
• DNA Double Strand Break Response (Sus scrofa)
• DNA Double Strand Break Response (Taeniopygia guttata)
• DNA Double Strand Break Response (Xenopus tropicalis)