ADPGK:Mg2+ phosphorylates Glc to G6P

Stable Identifier
R-HSA-5696021
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Glucose phosphorylation is a central event in cellular metabolism. ADP-dependent glucokinase (ADPGK) can phosphorylate glucose (Glc) using ADP as the phosphate donor to glucose 6-phopshate (G6P). To date, it has not been established whether this phosphorylation supports a significant role in priming glucose for a metabolic fate other than glycolysis (Richter et al. 2012). Stdies of metabolic changes during T cell activation suggest a role for it there (Kaminski et al. 2012).

Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
ADP-specific glucokinase activity of ADPGK:Mg2+ [extracellular region]
Physical Entity
Activity
Orthologous Events