AOC1 deaminates Hist

Stable Identifier
R-HSA-5696131
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Amiloride-sensitive, copper-containing amine oxidase (AOC1) can catalyse the oxidative deamination of diamines, particularly histamine (Hist) (McGrath et al. 2009). Histamine is involved in allergic and immune responses.

Literature References
PubMed ID Title Journal Year
19764817 Structure and inhibition of human diamine oxidase

McGrath, AP, Hilmer, KM, Collyer, CA, Shepard, EM, Elmore, BO, Brown, DE, Dooley, DM, Guss, JM

Biochemistry 2009
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
histamine oxidase activity of AOC1 dimer:2xCu2+:4xCa2+ [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created