Reactome: A Curated Pathway Database

LAIR2 binds collagen

Stable Identifier
R-HSA-5696357
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2 or CD306) a soluble homolog of LAIR1 protein, also has high affinity for various collagen molecules and this can interfere with collagen-dependent platelet aggregation and adhesion. LAIR-2 may function as a natural competitor for LAIR-1, thereby regulating its inhibitory potential (Lebbink et al. 2008, Lenting et al. 2010).

Literature References
Participants
Participant Of
Orthologous Events