STAMBPL1 is a deubiquitinase

Stable Identifier
R-HSA-5696547
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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STAMBPL1 (AMSH-LP) has Lys-63 deubiquitinase activity (Sato et al. 2008) and positively regulates TGF-beta signaling (Ibarolla et al. 2004) but unlike STAMBP (AMSH1) it does not bind STAM (Kikuchi et al. 2003).

Literature References
PubMed ID Title Journal Year
18758443 Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

Sato, Y, Yoshikawa, A, Yamagata, A, Mimura, H, Yamashita, M, Ookata, K, Nureki, O, Iwai, K, Komada, M, Fukai, S

Nature 2008
Participants
Participates
Catalyst Activity

Lys63-specific deubiquitinase activity of STAMBPL1 [cytosol]

This event is regulated
Positively by
Orthologous Events
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