TSEN complex cleaves the intron from pre-tRNA

Stable Identifier
R-HSA-5696813
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The TSEN complex endonucleolytically cleaves 5' and 3' of introns in tRNAs, leaving a 2',3' cyclic phosphate on the 5' exon and a 5' hydroxyl on the 3' exon (Paushkin et al. 2004, Trotta et al. 2006).

Participants
Participant Of
Event Information
Catalyst Activity
Catalyst Activity
Title
tRNA-specific ribonuclease activity of TSEN complex [nucleoplasm]
Physical Entity
Activity