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VDAC2 [mitochondrial outer membrane]
Stable Identifier
R-HSA-5696880
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Synonyms
Voltage-dependent anion-selective channel protein 2, VDAC2_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP30 deubiquitinates Ub-MOM proteins (Homo sapiens)
USP30:MOM proteins [mitochondrial outer membrane] (Homo sapiens)
MOM proteins [mitochondrial outer membrane] (Homo sapiens)
VDAC2 [mitochondrial outer membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Mitochondrial calcium ion transport (Homo sapiens)
VDAC1,2,3 translocate calcium from the cytosol to the mitochondrial intermembrane space (Homo sapiens)
VDAC1,2,3 [mitochondrial outer membrane] (Homo sapiens)
VDAC2 [mitochondrial outer membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P45880 VDAC2
Gene Names
VDAC2
Chain
initiator methionine:, chain:2-294
Reference Genes
BioGPS Gene:7417 VDAC2
COSMIC (genes):VDAC2 VDAC2
CTD Gene:7417 VDAC2
dbSNP Gene:7417 VDAC2
ENSEMBL:ENSG00000165637 VDAC2
HGNC:12672 VDAC2
KEGG:hsa:7417 VDAC2
Monarch:7417 VDAC2
NCBI Gene:7417 VDAC2
OMIM:193245 VDAC2
UCSC:P45880 VDAC2
Reference Transcript
RefSeq:NM_001184783.2 VDAC2
RefSeq:NM_003375.4 VDAC2
RefSeq:NM_001184823.1 VDAC2
RefSeq:NM_001324088.1 VDAC2
Other Identifiers
11748509_s_at
11756232_s_at
16706298
211662_PM_s_at
211662_s_at
2485777
2485778
2485779
2485780
2485781
2485783
3252578
3252582
3252583
3252584
3252585
3252586
3252587
3252588
3252589
3252590
3252591
3252592
3252593
3252594
3252595
3252596
3252598
3252599
3252600
3252601
3252603
3252604
3252606
3252607
3252608
3252609
3252610
37696_at
37697_s_at
7417
7928524
8042335
A_14_P112950
A_14_P130818
A_23_P75268
A_32_P41292
A_33_P3415037
GE57592
GE84830
GO:0000166
GO:0001669
GO:0005215
GO:0005515
GO:0005524
GO:0005634
GO:0005739
GO:0005741
GO:0006811
GO:0006820
GO:0006869
GO:0007005
GO:0007339
GO:0008142
GO:0008289
GO:0008308
GO:0015288
GO:0015485
GO:0016020
GO:0017121
GO:0017128
GO:0031210
GO:0031410
GO:0031966
GO:0032272
GO:0042645
GO:0043226
GO:0043227
GO:0045332
GO:0046930
GO:0055085
GO:0061024
GO:0097001
GO:0097225
GO:0097345
GO:0098656
GO:1990542
GO:2001243
HMNXSV003044406
ILMN_2221066
L08666_at
PH_hs_0029855
PH_hs_0032834
PH_hs_0039186
TC10000485.hg
TC10002137.hg
g190199_3p_s_at
Participates
as a candidate of
MOM proteins [mitochondrial outer membrane] (Homo sapiens)
as a member of
VDAC1,2,3 [mitochondrial outer membrane] (Homo sapiens)
Other forms of this molecule
p-S65-Ub:VDAC2 [mitochondrial outer membrane]
K63polyUb-VDAC2 [mitochondrial outer membrane]
K48polyUb-VDAC2 [mitochondrial outer membrane]
Ub-VDAC2 [mitochondrial outer membrane]
PolyUb-VDAC2 [mitochondrial outer membrane]
Inferred To
Porin2 [mitochondrial outer membrane]
(Drosophila melanogaster)
vdac-1 [mitochondrial outer membrane]
(Caenorhabditis elegans)
CG31722 [mitochondrial outer membrane]
(Drosophila melanogaster)
CG31722-B [mitochondrial outer membrane]
(Drosophila melanogaster)
VDAC2 [mitochondrial outer membrane]
(Bos taurus)
VDAC2 [mitochondrial outer membrane]
(Canis familiaris)
VDAC2 [mitochondrial outer membrane]
(Gallus gallus)
VDAC2 [mitochondrial outer membrane]
(Mus musculus)
VDAC2 [mitochondrial outer membrane]
(Rattus norvegicus)
VDAC2 [mitochondrial outer membrane]
(Schizosaccharomyces pombe)
VDAC2 [mitochondrial outer membrane]
(Sus scrofa)
vdac2 [mitochondrial outer membrane]
(Danio rerio)
vdac2 [mitochondrial outer membrane]
(Xenopus tropicalis)
porin [mitochondrial outer membrane]
(Drosophila melanogaster)
Homologues of VDAC2 [mitochondrial outer membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001171752.1
,
NP_001311017.1
,
NP_001171712.1
,
NP_003366.2
OpenTargets
ENSG00000165637
ENSEMBL
ENSP00000361635
,
ENSP00000443092
,
ENST00000313132
,
ENST00000332211
,
ENST00000543351
,
ENSP00000361686
HPA
ENSG00000165637-VDAC2
ZINC - Substances
VDAC2_HUMAN
ZINC target
P45880
PRO
P45880
Pharos - Targets
P45880
GlyGen
P45880
ZINC - Predictions - Purchasable
VDAC2_HUMAN
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
22
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.64
10
UniProt:P21796 VDAC1
7
p-S65-Ub:VDAC1 [mitochondrial outer membrane]
(R-HSA-9834991)
K63polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834037)
K48polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-5205624)
Ub-VDAC1 [mitochondrial outer membrane]
(R-HSA-9834989)
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
VDAC1 [mitochondrial intermembrane space]
(R-HSA-1267960)
PolyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-6783079)
0.623
6
UniProt:P49821 NDUFV1
1
NDUFV1 [mitochondrial inner membrane]
(R-HSA-163926)
0.556
3
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:P07196 NEFL
1
NEFL [cytosol]
(R-HSA-432284)
0.556
3
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.536
2
UniProt:P27824 CANX
2
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
0.527
2
UniProt:P04578 env
7
ENV [viral envelope]
(R-HIV-173439)
Surface protein gp120 [viral envelope]
(R-HIV-171211)
Transmembrane protein gp41 [viral envelope]
(R-HIV-171195)
Envelope glycoprotein gp160 [endoplasmic reticulum membrane]
(R-HIV-189343)
Glycosylated Envelope glycoprotein gp160 [Golgi membrane]
(R-HIV-3149443)
Transmembrane protein gp41 (P04578) [cytosol]
(R-HIV-189359)
Surface protein gp120 (P04578) [cytosol]
(R-HIV-189269)
0.462
2
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