USP33 deubiquitinates CCP110,ARRB

Stable Identifier
R-HSA-5696945
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

USP33 regulates centrosome duplication by mediating deubiquitination and stabilization of CCP110 in S and G2/M phase (Li et al. 2013) and regulates G-protein coupled receptor (GPCR) signaling by deubiquitinating beta-arrestins (ARRB1 and ARRB2) (Shenoy et al. 2009).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
thiol-dependent ubiquitinyl hydrolase activity of USP33:PolyUb-CCP110,PolyUb-ARRB1,PolyUb-ARRB2 [cytosol]
Physical Entity
Activity
Orthologous Events