Reactome | NDUFB6 [mitochondrial inner membrane]

NDUFB6 [mitochondrial inner membrane]

Stable Identifier

R-HSA-59938

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase B17 subunit , Complex I-B17, CI-B17

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O95139 NDUFB6

Gene Names

NDUFB6

Chain

initiator methionine:, chain:2-128

Reference Genes

BioGPS Gene:4712 NDUFB6

COSMIC (genes):NDUFB6 NDUFB6

CTD Gene:4712 NDUFB6

dbSNP Gene:4712 NDUFB6

ENSEMBL:ENSG00000165264 NDUFB6

ENSEMBL_homo_sapiens_GENE:ENSG00000165264.11 NDUFB6

HGNC:7701 NDUFB6

KEGG Gene (Homo sapiens):4712 NDUFB6

Monarch:4712 NDUFB6

NCBI Gene:4712 NDUFB6

OMIM:603322 NDUFB6

UCSC:O95139 NDUFB6

Reference Transcript

Other Identifiers

11717670_a_at

11741789_a_at

17093122

203613_PM_s_at

203613_s_at

2562195

3203157

3203158

3203159

3203163

3203164

3203165

3203166

3203169

3203179

3203184

3203185

3203186

38979_at

4712

64358_s_at

8160587

A_21_P0000148

A_23_P43613

GE61784

GO:0003824

GO:0005215

GO:0005515

GO:0005634

GO:0005654

GO:0005739

GO:0005743

GO:0005747

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0016020

GO:0016491

GO:0031966

GO:0032981

GO:0042775

GO:0042776

GO:0043226

GO:0055086

GO:0065003

GO:0070469

GO:1901135

HMNXSV003029106

HMNXSV003045554

Hs2.376564.1.S1_3p_s_at

ILMN_1763147

ILMN_2369924

PH_hs_0006049

TC09001001.hg

g4505364_3p_a_at

Participates

as a member of

Substrate of YME1L1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as an input of

COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex (Homo sapiens)

as a component of

Inferred To

ndufb6 [mitochondrial inner membrane] (Danio rerio)

ndufb6 [mitochondrial inner membrane] (Xenopus tropicalis)

Ghost homologue of NDUFB6 [mitochondrial inner membrane] (Caenorhabditis elegans)

Ghost homologue of NDUFB6 [mitochondrial inner membrane] (Drosophila melanogaster)

NDUFB6 [mitochondrial inner membrane] (Bos taurus)

NDUFB6 [mitochondrial inner membrane] (Canis familiaris)

NDUFB6 [mitochondrial inner membrane] (Gallus gallus)

NDUFB6 [mitochondrial inner membrane] (Sus scrofa)

Ndufb6 [mitochondrial inner membrane] (Mus musculus)

Ndufb6 [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_002484.1, NP_877416.1

OpenTargets

ENSG00000165264

HPA

ENSG00000165264-NDUFB6

GeneCards

O95139

Ensembl

ENSP00000297983, ENST00000379847, ENSP00000369176, ENST00000350021, ENSG00000165264

PRO

O95139

Pharos - Targets

O95139

PDB

5XTH, 5XTD, 5XTI, 5XTC

HMDB Protein

HMDBP00195

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.643	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q9GZM5 YIPF3			0.527	2
UniProt:O43674 NDUFB5	1	NDUFB5 [mitochondrial inner membrane] (R-HSA-163944)	0.527	3
UniProt:P51970 NDUFA8	1	NDUFA8 [mitochondrial inner membrane] (R-HSA-60627)	0.527	2
UniProt:O75380 NDUFS6	1	NDUFS6 [mitochondrial inner membrane] (R-HSA-163922)	0.527	4
UniProt:P19526 FUT1	1	FUT1 [Golgi membrane] (R-HSA-9034059)	0.527	2
UniProt:O43920 NDUFS5	1	NDUFS5 [mitochondrial inner membrane] (R-HSA-60226)	0.527	3