Reactome | MT-ND6 [mitochondrial inner membrane]

MT-ND6 [mitochondrial inner membrane]

Stable Identifier

R-HSA-60569

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3)

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Locations in the PathwayBrowser for interactor UniProt:O75489%20NDUFS3

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External Reference Information

External Reference

UniProt:P03923 MT-ND6

Gene Names

MT-ND6, MTND6, NADH6, ND6

Chain

chain:1-174

Reference Genes

BioGPS Gene:4541 MT-ND6

COSMIC (genes):MT-ND6 MT-ND6

CTD Gene:4541 MT-ND6

dbSNP Gene:4541 MT-ND6

ENSEMBL:ENSG00000198695 MT-ND6

ENSEMBL_homo_sapiens_GENE:ENSG00000198695.2 MT-ND6

HGNC:7462 MT-ND6

KEGG Gene (Homo sapiens):4541 MT-ND6

Monarch:4541 MT-ND6

NCBI Gene:4541 MT-ND6

OMIM:516006 MT-ND6

Reference Transcript

RefSeq:NC_012920.1 MT-ND6

Other Identifiers

1553575_PM_at

1553575_at

17100697

17100699

2867408

4037740

4037741

4037742

4037743

4037744

4037745

4037746

4037747

4037748

4037749

4037750

4037751

4037752

4037753

4037754

4541

8113120

8165705

8165707

A_23_P317056

GO:0003824

GO:0005215

GO:0005739

GO:0005743

GO:0005747

GO:0006091

GO:0006120

GO:0007005

GO:0008137

GO:0009060

GO:0016020

GO:0016491

GO:0031966

GO:0032981

GO:0042776

GO:0043226

GO:0055086

GO:0065003

GO:0070469

GO:1901135

HMNXSV003052833

Hs2Affx.1.46.S1_3p_at

RNA143503|tRNA_420_69

RNA147303|p0407_imsncRNA822

Participates

as a member of

Substrate of YME1L1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)

as an input of

COA1:MT-ND2, TMEM186:MT-ND3, MT-ND6, NDUFB6 bind the MCIA complex to form a 370kDa subcomplex (Homo sapiens)

as a component of

Inferred To

Ghost homologue of MT-ND6 [mitochondrial inner membrane] (Caenorhabditis elegans)

Ghost homologue of MT-ND6 [mitochondrial inner membrane] (Canis familiaris)

Mtnd6 [mitochondrial inner membrane] (Mus musculus)

Mtnd6 [mitochondrial inner membrane] (Rattus norvegicus)

mt:ND6 [mitochondrial inner membrane] (Drosophila melanogaster)

MT-ND6 [mitochondrial inner membrane] (Bos taurus)

MT-ND6 [mitochondrial inner membrane] (Gallus gallus)

MT-ND6 [mitochondrial inner membrane] (Sus scrofa)

mt-nd6 [mitochondrial inner membrane] (Danio rerio)

mt-nd6 [mitochondrial inner membrane] (Xenopus tropicalis)

Cross References

RefSeq

YP_003024037.1

OpenTargets

ENSG00000198695

GeneCards

P03923

HPA

ENSG00000198695-MT-ND6

Ensembl

ENSG00000198695, ENSP00000354665, ENST00000361681

PRO

P03923

Pharos - Targets

P03923

Orphanet

16484

HMDB Protein

HMDBP00189

PDB

5XTC, 5XTD

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75489 NDUFS3	2	NDUFS3 [mitochondrial matrix] (R-HSA-163927) NDUFS3 [cytosol] (R-HSA-9714751)	0.527	2