Reactome | OIP5 [nucleoplasm]

OIP5 [nucleoplasm]

Stable Identifier

R-HSA-606286

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein Mis18-beta, MS18B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43482 OIP5

Gene Names

OIP5, MIS18B

Chain

chain:1-229

Reference Genes

BioGPS Gene:11339 OIP5

COSMIC (genes):OIP5 OIP5

CTD Gene:11339 OIP5

dbSNP Gene:11339 OIP5

ENSEMBL:ENSG00000104147 OIP5

HGNC:20300 OIP5

KEGG:hsa:11339 OIP5

Monarch:11339 OIP5

NCBI Gene:11339 OIP5

OMIM:606020 OIP5

UCSC:O43482 OIP5

Reference Transcript

Other Identifiers

11339

11727543_at

16807605

213599_PM_at

213599_at

3619946

3619947

3619950

3619952

3619953

3619954

3619955

3619956

37474_at

7987636

A_23_P379614

GE54193

GO:0000775

GO:0000785

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0007059

GO:0007154

GO:0010369

GO:0015030

GO:0016607

GO:0034080

GO:0042802

GO:0043226

GO:0043231

GO:0046872

GO:0051301

HMNXSV003055540

Hs.116206.0.S1_3p_at

ILMN_1759277

ILMN_2196984

PH_hs_0011268

TC15001248.hg

Participates

as a component of

Mis18 Complex [nucleoplasm] (Homo sapiens)

Inferred To

oip5 [nucleoplasm] (Xenopus tropicalis)

Oip5 [nucleoplasm] (Rattus norvegicus)

OIP5 [nucleoplasm] (Bos taurus)

OIP5 [nucleoplasm] (Canis familiaris)

OIP5 [nucleoplasm] (Gallus gallus)

OIP5 [nucleoplasm] (Mus musculus)

OIP5 [nucleoplasm] (Sus scrofa)

Cross References

ENSEMBL

ENST00000220514, ENSP00000220514

OpenTargets

ENSG00000104147

HPA

ENSG00000104147-OIP5

PRO

O43482

Pharos - Targets

O43482

PDB

7SFY

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.718	6
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P20618 PSMB1	7	PSMB1 [cytosol] (R-HSA-68738) PSMB1 [nucleoplasm] (R-HSA-174347) PSMB1 [secretory granule lumen] (R-HSA-6803287) PSMB1 [extracellular region] (R-HSA-6806477) PSMB1 [ficolin-1-rich granule lumen] (R-HSA-6803340) pro-PSMB1 [cytosol] (R-HSA-9908139) PSMB1(1-28) [cytosol] (R-HSA-9908143)	0.556	3
UniProt:Q15915 ZIC1	1	ZIC1 [nucleoplasm] (R-HSA-9731648)	0.556	5
UniProt:Q96EV8 DTNBP1	1	DTNBP1 [cytosol] (R-HSA-429819)	0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [cytosol] (R-HSA-162411) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:Q8TCT0 CERK	1	CERK [plasma membrane] (R-HSA-1631584)	0.556	3
UniProt:Q13227 GPS2	1	GPS2 [nucleoplasm] (R-HSA-351642)	0.556	5
UniProt:Q9BXU0 TEX12	1	TEX12 [nucleoplasm] (R-HSA-912441)	0.556	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	3
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.556	3
UniProt:Q9NQ94 A1CF	1	A1CF [nucleoplasm] (R-HSA-3211440)	0.556	3
UniProt:Q9HAQ2 KIF9	1	KIF9 [cytosol] (R-HSA-984616)	0.556	3
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.556	3
UniProt:O14561 NDUFAB1	4	octanoyl-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-9857608) NDUFAB1 [mitochondrial inner membrane] (R-HSA-163925) PPANT-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-8933545) Mal-PPANT-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-8934586)	0.556	3
UniProt:Q9NPD8 UBE2T	3	UBE2T [nucleoplasm] (R-HSA-420942) MonoUb-K91,K182-UBE2T [nucleoplasm] (R-HSA-6785362) Ub-C86-UBE2T [nucleoplasm] (R-HSA-8864217)	0.527	2
UniProt:Q9Y6A5 TACC3	1	TACC3 [cytosol] (R-HSA-2160956)	0.527	2
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.502	2

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