Reactome | OPRM1 [plasma membrane]

OPRM1 [plasma membrane]

Stable Identifier

R-HSA-60951

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Mu-type opioid receptor, MOR-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P35372 OPRM1

Gene Names

OPRM1, MOR1

Chain

chain:1-400

Reference Genes

COSMIC (genes):OPRM1 OPRM1

dbSNP Gene:4988 OPRM1

ENSEMBL:ENSG00000112038 OPRM1

Participates

as a member of

as an output of

as an input of

Opioid binds MOR (Homo sapiens)

as a component of

Opioid:MOR [plasma membrane] (Homo sapiens)

Inferred To

npr-16 [plasma membrane] (Caenorhabditis elegans)

npr-26 [plasma membrane] (Caenorhabditis elegans)

AstC-R1 [plasma membrane] (Drosophila melanogaster)

oprm1 [plasma membrane] (Xenopus tropicalis)

AstC-R2 [plasma membrane] (Drosophila melanogaster)

OPRM1 [plasma membrane] (Bos taurus)

OPRM1 [plasma membrane] (Caenorhabditis elegans)

OPRM1 [plasma membrane] (Canis familiaris)

OPRM1 [plasma membrane] (Gallus gallus)

OPRM1 [plasma membrane] (Sus scrofa)

npr-23 [plasma membrane] (Caenorhabditis elegans)

Rh7 [plasma membrane] (Drosophila melanogaster)

Homologues of OPRM1 [plasma membrane] (Caenorhabditis elegans)

Homologues of OPRM1 [plasma membrane] (Drosophila melanogaster)

npr-24 [plasma membrane] (Caenorhabditis elegans)

npr-28 [plasma membrane] (Caenorhabditis elegans)

npr-18 [plasma membrane] (Caenorhabditis elegans)

Oprm1 [plasma membrane] (Mus musculus)

Oprm1 [plasma membrane] (Rattus norvegicus)

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5T9L3 WLS	5	WLS [extracellular exosome] (R-HSA-3781960) WLS [endocytic vesicle membrane] (R-HSA-3781954) WLS [early endosome membrane] (R-HSA-3247745) WLS [Golgi membrane] (R-HSA-3247747) WLS [plasma membrane] (R-HSA-3247746)	0.819	11
UniProt:Q96S59 RANBP9	1	RANBP9 [cytosol] (R-HSA-374586)	0.69	5
UniProt:Q9P0L0 VAPA	4	VAPA [azurophil granule membrane] (R-HSA-6799364) VAPA [plasma membrane] (R-HSA-6806269) VAPA [endoplasmic reticulum membrane] (R-HSA-429677) VAPA [cytosol] (R-HSA-9609920)	0.675	4
UniProt:P35212 GJA4	1	GJA4 [endoplasmic reticulum membrane] (R-HSA-190657)	0.635	3
UniProt:P21333 FLNA	3	FLNA [extracellular region] (R-HSA-350712) p-S2152-FLNA [cytosol] (R-HSA-5669246) FLNA [cytosol] (R-HSA-210019)	0.602	5
UniProt:Q8TEW6 DOK4	1	DOK4 [cytosol] (R-HSA-8847701)	0.581	4
UniProt:Q9Y679 AUP1			0.581	4
UniProt:Q92905 COPS5	2	COPS5 [nucleoplasm] (R-HSA-5697019) COPS5 [cytosol] (R-HSA-416963)	0.581	5
UniProt:Q8IUQ4 SIAH1	1	SIAH1 [cytosol] (R-HSA-374563)	0.581	4
UniProt:Q9H3P2 NELFA	1	NELFA [nucleoplasm] (R-HSA-112426)	0.508	2
UniProt:O43255 SIAH2	1	SIAH2 [cytosol] (R-HSA-374566)	0.508	3
UniProt:Q15942 ZYX			0.508	2
UniProt:Q9H3M0 KCNF1	1	KCNF1 [plasma membrane] (R-HSA-977450)	0.488	2