Postsynaptic nicotinic acetylcholine receptors

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R-HSA-622327
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Pathway
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Homo sapiens
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Nicotinic acetylcholine receptors are found in the postsynaptic terminals and these receptors are responsible in mediating postsynaptic currents. Most common types of postsynaptic nicotinic acetylcholine receptors are homomeric alpha 7 containing acetylcholine receptors. The densities of acetylcholine receptors are found to be similar to NMDA and AMPA receptors at these sites. Nicotinic acetylcholine receptors may permit both sodium and calcium ions, however, the ratio of sodium and calcium influx makes the receptors either highly sodium permeable or highly calcium permeable.

Literature References
PubMed ID Title Journal Year
17689497 Regulation of synaptic transmission and plasticity by neuronal nicotinic acetylcholine receptors

McKay, BE, Placzek, AN, Dani, JA

Biochem Pharmacol 2007
17009926 Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

Dani, JA, Bertrand, D

Annu Rev Pharmacol Toxicol 2007
12036180 Nicotinic acetylcholine receptors in autonomic ganglia

Skok, VI

Auton Neurosci 2002
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