Highly sodium permeable acetylcholine nicotinic receptors

Stable Identifier
R-HSA-629587
Type
Pathway
Species
Homo sapiens
Compartment
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Nicotinic acetylcholne receptors that have low Ca2+ permeability allow the influx of Na+ which causes depolarization of the membrane initiating voltage dependent responses such as activation of voltage dependent opening of Ca2+ channels and thus eliciting an increase in Ca2+ and downstream signaling. These receptors could be found in both presynaptic and postsynaptic terminals.

Literature References
PubMed ID Title Journal Year
9110108 Nicotine and sympathetic neurotransmission

Haass, M, K├╝bler, W

Cardiovasc Drugs Ther 1997
Participants
Participant Of
Orthologous Events
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Created