Activation of highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Stable Identifier
R-HSA-629595
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Acetylcholine binding activates postsynaptic acetylchloine receptors that show Ca2+ currents which facilitate the process of long term potentiation (LTP).

Literature References
PubMed ID Title Journal Year
12810063 Fractional Ca(2+) current through human neuronal alpha7 nicotinic acetylcholine receptors

Fucile, S, Renzi, M, Lax, P, Eusebi, F

Cell Calcium 2003
10945867 Evidence that nicotinic alpha(7) receptors are not involved in the hyperlocomotor and rewarding effects of nicotine

Grottick, AJ, Trube, G, Corrigall, WA, Huwyler, J, Malherbe, P, Wyler, R, Higgins, GA

J Pharmacol Exp Ther 2000
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ligand-gated ion channel activity of O-acteylcholine bound to calcium permeable postsynaptic nicotinic acetylcholine receptors [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created