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STAT1 [cytosol]
Stable Identifier
R-HSA-629622
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Signal transducer and activator of transcription 1-alpha/beta, STAT1_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to mechanical stimuli (Homo sapiens)
Response of endothelial cells to shear stress (Homo sapiens)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Homo sapiens)
Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
TYK2-dependent STAT1 and STAT3 phosphorylation (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by KIT in disease (Homo sapiens)
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Recruitment of STATs by KIT mutants (Homo sapiens)
KIT mutant dimers:SFKs:p-JAK2:STATs [plasma membrane] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by PDGFR in disease (Homo sapiens)
Signaling by PDGFRA extracellular domain mutants (Homo sapiens)
STAT binds to p-11Y PDGFRA extracellular domain dimers (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
p-11Y PDGFRA extracellular domain dimer:STAT [endoplasmic reticulum membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants (Homo sapiens)
STAT binds to the mutant PDGFRA receptor (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
p-11Y PDGFRA mutant receptor dimer:STAT [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
Phosphorylation of STAT1 (Homo sapiens)
STAT1,STAT2:N [cytosol] (Homo sapiens)
STAT1,STAT2 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
SARS-CoV-2 N protein binds STAT1, STAT2 (Homo sapiens)
STAT1,STAT2 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT2:N [cytosol] (Homo sapiens)
STAT1,STAT2 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by RUNX2 (Homo sapiens)
Regulation of RUNX2 expression and activity (Homo sapiens)
RUNX2 binds STAT1 (Homo sapiens)
RUNX2:STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
RUNX2 translocates to the nucleus (Homo sapiens)
RUNX2:STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Growth hormone receptor signaling (Homo sapiens)
JAK2 binds STAT1/3 (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:STAT1/STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
JAK2 phosphorylates STAT1/STAT3 (Homo sapiens)
Growth Hormone: Activated Growth Hormone Receptor:p(Y1007)-JAK2 dimer:STAT1/STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
ISGylation of host proteins (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Regulation of protein ISGylation by ISG15 deconjugating enzyme USP18 (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
ISGylated host proteins [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
PKR-mediated signaling (Homo sapiens)
PKR forms a dimer (Homo sapiens)
STAT1,STAT3:EIF2AK2 [cytosol] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3 binds PKR (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3:EIF2AK2 [cytosol] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Phosphorylation of STAT1 (Homo sapiens)
STAT1,STAT2:N [cytosol] (Homo sapiens)
STAT1,STAT2 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by CSF3 (G-CSF) (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds STAT1,3,5 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:STAT1,3,5 [plasma membrane] (Homo sapiens)
STAT1, STAT3, STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1, STAT3, STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:STAT1,3,5 [plasma membrane] (Homo sapiens)
STAT1, STAT3, STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-12 family signaling (Homo sapiens)
Interleukin-27 signaling (Homo sapiens)
STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Homo sapiens)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Homo sapiens)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor (Homo sapiens)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interleukin-35 Signalling (Homo sapiens)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Homo sapiens)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Homo sapiens)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Homo sapiens)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Homo sapiens)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Homo sapiens)
IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] (Homo sapiens)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 associates with IL6ST:IL6ST (Homo sapiens)
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Homo sapiens)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin-21 signaling (Homo sapiens)
IL21 receptor STAT binding (Homo sapiens)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Homo sapiens)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IL21 receptor STAT phosphorylation (Homo sapiens)
IL21:IL21R:p-Y-JAK1:IL2RG:p-Y-JAK3:STAT1,STAT3,STAT4,STAT5 [plasma membrane] (Homo sapiens)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interleukin-9 signaling (Homo sapiens)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3 binds STAT1, STAT3, STAT5A or STAT5B (Homo sapiens)
IL9:p-Y407-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT1,STAT3,STAT5A,STAT5B [plasma membrane] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interleukin-20 family signaling (Homo sapiens)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Homo sapiens)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Homo sapiens)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IFNL1:p-Y434,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2 binds STAT1, STAT2, STAT3, STAT4, STAT5 (Homo sapiens)
IFNL1:p-Y343-Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1,STAT2, STAT3, STAT4, STAT5 [plasma membrane] (Homo sapiens)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IL24:p-IL20RA:p-JAK1:IL20RB binds STAT1,STAT3 (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1 binds STAT1, STAT3 (Homo sapiens)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Homo sapiens)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
Expression of STAT3-upregulated cytosolic proteins (Homo sapiens)
STAT3-upregulated cytosolic proteins [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT6 bind IL13:IL13R type II (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Homo sapiens)
STAT1,STAT3,STAT6 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT6 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT6 phosphorylation (Homo sapiens)
IL13-bound tyrosine-phosphorylated IL13 receptor type II with STAT1,STAT3,STAT6 [plasma membrane] (Homo sapiens)
STAT1,STAT3,STAT6 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Interleukin-6 family signaling (Homo sapiens)
Interleukin-6 signaling (Homo sapiens)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Homo sapiens)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PDGF (Homo sapiens)
Downstream signal transduction (Homo sapiens)
STAT binds to the active receptor (Homo sapiens)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Homo sapiens)
STAT family members [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
STAT family members [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Signaling by SCF-KIT (Homo sapiens)
Phosphorylation of STATs (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
Recruitment of STATs (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P42224 STAT1
Gene Names
STAT1
Chain
initiator methionine:, chain:2-750
Reference Genes
ENSEMBL:ENSG00000115415 STAT1
Participates
as an input of
STAT1 associates with IL6ST:IL6ST (Homo sapiens)
STAT1 and STAT4 associate with IL12RB2:IL6ST receptor (Homo sapiens)
STAT1,STAT3 associate with IL27RA:IL12RB2 receptor (Homo sapiens)
STAT1, STAT3 bind p-Y611-IL27RA from Interleukin-27:Interleukin-27 receptor complex (Homo sapiens)
Phosphorylation of STAT1 on tyrosine-701 is enhanced by p-S172-IKBKE (Homo sapiens)
RUNX2 binds STAT1 (Homo sapiens)
as a component of
IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane] (Homo sapiens)
STAT1:IL12A:EBI3:IL6ST:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] (Homo sapiens)
IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-Y-TYK2:STAT1:STAT3 [plasma membrane] (Homo sapiens)
RUNX2:STAT1 [cytosol] (Homo sapiens)
as a member of
STAT3-upregulated cytosolic proteins [cytosol] (Homo sapiens)
STAT1,STAT3,STAT6 [cytosol] (Homo sapiens)
STAT1, STAT2, STAT3, STAT4, STAT5 [cytosol] (Homo sapiens)
STAT1, STAT3, STAT5 [cytosol] (Homo sapiens)
STAT1,STAT3,STAT4,STAT5 [cytosol] (Homo sapiens)
ISG15 targets [cytosol] (Homo sapiens)
STAT1, STAT3 [cytosol] (Homo sapiens)
STAT family members [cytosol] (Homo sapiens)
STATs [cytosol] (Homo sapiens)
STAT1,STAT2 [cytosol] (Homo sapiens)
Other forms of this molecule
p-Y701-STAT1 [cytosol]
p-Y701-STAT1 [nucleoplasm]
p-Y701-STAT1 [cytosol]
p-Y701-STAT1 [nucleoplasm]
p-Y701,S727-STAT1 [cytosol]
p-STAT1 [cytosol]
p-STAT1 [nucleoplasm]
Inferred To
stat1 [cytosol]
(Xenopus tropicalis)
dstD [cytosol]
(Dictyostelium discoideum)
stat1a [cytosol]
(Danio rerio)
dstC [cytosol]
(Dictyostelium discoideum)
sta-2 [cytosol]
(Caenorhabditis elegans)
dstB [cytosol]
(Dictyostelium discoideum)
STAT1 [cytosol]
(Bos taurus)
STAT1 [cytosol]
(Caenorhabditis elegans)
STAT1 [cytosol]
(Canis familiaris)
STAT1 [cytosol]
(Dictyostelium discoideum)
STAT1 [cytosol]
(Gallus gallus)
STAT1 [cytosol]
(Sus scrofa)
Stat92E [cytosol]
(Drosophila melanogaster)
Homologues of STAT1 [cytosol]
(Caenorhabditis elegans)
Homologues of STAT1 [cytosol]
(Dictyostelium discoideum)
dstA [cytosol]
(Dictyostelium discoideum)
Stat1 [cytosol]
(Mus musculus)
Stat1 [cytosol]
(Rattus norvegicus)
sta-1 [cytosol]
(Caenorhabditis elegans)
Interactors (40)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P52630 STAT2
4
p-Y690-STAT2 [cytosol]
(R-HSA-909683)
STAT2 [cytosol]
(R-HSA-882029)
p-Y690-STAT2 [nucleoplasm]
(R-HSA-909673)
p-Y-STAT2 [cytosol]
(R-HSA-8987235)
0.92
19
UniProt:P40763 STAT3
12
p-Y705-STAT3 [nucleoplasm]
(R-HSA-1112554)
p-Y705-STAT3 [cytosol]
(R-HSA-914048)
STAT3 [cytosol]
(R-HSA-539044)
p-Y705-STAT3 [cytosol]
(R-HSA-8983130)
p-Y705,S727-STAT3 [cytosol]
(R-HSA-539048)
p-S727-STAT3 [cytosol]
(R-HSA-198705)
p-Y705-STAT3 [nucleoplasm]
(R-HSA-9027589)
p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701429)
AcK685- p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701435)
p-STAT3 [cytosol]
(R-HSA-8982823)
p-STAT3 [nucleoplasm]
(R-HSA-8983188)
Unfolded STAT3 [cytosol]
(R-HSA-6813811)
0.908
10
UniProt:P00533 EGFR
20
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR A767_V769dup [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR N771_H773dup [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR K739_I744dup [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
0.774
7
UniProt:P23458 JAK1
6
p-Y-JAK1 [cytosol]
(R-HSA-451921)
JAK1 [cytosol]
(R-HSA-451898)
p-Y1034-JAK1 [cytosol]
(R-HSA-1112543)
p-JAK1 [cytosol]
(R-HSA-8950711)
JAK1 [endosome]
(R-HSA-8983168)
p-Y1034,Y1035-JAK1 [cytosol]
(R-HSA-9005335)
0.757
6
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.706
6
UniProt:P15260 IFNGR1
2
IFNGR1 [plasma membrane]
(R-HSA-629623)
p-Y457-IFNGR1 [plasma membrane]
(R-HSA-873798)
0.69
4
IntAct:EBI-9984951 IRF1
0.669
3
UniProt:Q8N9N8 EIF1A
0.666
4
UniProt:P42224 STAT1
8
STAT1 [cytosol]
(R-HSA-629622)
p-Y701-STAT1 [cytosol]
(R-HSA-3132766)
p-Y701-STAT1 [nucleoplasm]
(R-HSA-6788624)
p-Y701-STAT1 [cytosol]
(R-HSA-8951202)
p-Y701-STAT1 [nucleoplasm]
(R-HSA-8985905)
p-Y701,S727-STAT1 [cytosol]
(R-HSA-9850842)
p-STAT1 [cytosol]
(R-HSA-8950418)
p-STAT1 [nucleoplasm]
(R-HSA-8987140)
0.643
4
UniProt:P52294 KPNA1
2
KPNA1 [cytosol]
(R-HSA-180612)
KPNA1 [nucleoplasm]
(R-HSA-188865)
0.623
4
UniProt:Q7Z434 MAVS
2
MAVS [mitochondrial outer membrane]
(R-HSA-913730)
K48polyUb-MAVS [mitochondrial outer membrane]
(R-HSA-983463)
0.576
3
UniProt:P04626 ERBB2
20
ERBB2 G309E [plasma membrane]
(R-HSA-9665342)
ERBB2 G309A [plasma membrane]
(R-HSA-9665349)
ERBB2 S310F [plasma membrane]
(R-HSA-9665350)
ERBB2 S310Y [plasma membrane]
(R-HSA-9665344)
p-6Y-ERBB2 G309A [plasma membrane]
(R-HSA-9665381)
p-6Y-ERBB2 G309E [plasma membrane]
(R-HSA-9665382)
p-6Y-ERBB2 S310F [plasma membrane]
(R-HSA-9665379)
p-6Y-ERBB2 S310Y [plasma membrane]
(R-HSA-9665385)
p-Y-ERBB2 L755P [plasma membrane]
(R-HSA-9654268)
p-Y-ERBB2 I767M [plasma membrane]
(R-HSA-9654303)
p-Y-ERBB2 T798I [plasma membrane]
(R-HSA-9654618)
p-Y-ERBB2 Y772_A775dup [plasma membrane]
(R-HSA-9665652)
p-Y-ERBB2 T862A [plasma membrane]
(R-HSA-9654695)
p-Y-ERBB2 T798M [plasma membrane]
(R-HSA-9654615)
p-Y-ERBB2 H878Y [plasma membrane]
(R-HSA-9654833)
p-Y-ERBB2 V777L [plasma membrane]
(R-HSA-9654401)
p-Y-ERBB2 L755S [plasma membrane]
(R-HSA-9654194)
p-Y-ERBB2 V777E [plasma membrane]
(R-HSA-9654397)
p-Y-ERBB2 V777M [plasma membrane]
(R-HSA-9654398)
p-Y-ERBB2 L755M [plasma membrane]
(R-HSA-9654191)
0.571
3
IntAct:EBI-10178797 4005
0.556
3
UniProt:Q01804 OTUD4
0.556
3
UniProt:Q13813 SPTAN1
6
SPTAN1 [cytosol]
(R-HSA-201601)
SPTAN1(1-1185) [cytosol]
(R-HSA-202944)
SPTAN1(1186-2472) [cytosol]
(R-HSA-202964)
SPTAN1 [specific granule lumen]
(R-HSA-6799533)
SPTAN1 [extracellular region]
(R-HSA-6806322)
SPTAN1 [tertiary granule lumen]
(R-HSA-6800874)
0.547
2
UniProt:P07239 DUSP
0.544
2
UniProt:P03255-2
0.544
2
UniProt:P01100 FOS
2
FOS [nucleoplasm]
(R-HSA-450216)
p-T325,T331,S362,S374-FOS [nucleoplasm]
(R-HSA-450283)
0.536
6
UniProt:Q14765 STAT4
4
p-Y693-STAT4 [nucleoplasm]
(R-HSA-8950636)
p-STAT4 [cytosol]
(R-HSA-8950350)
p-Y693-STAT4 [cytosol]
(R-HSA-8950343)
STAT4 [cytosol]
(R-HSA-8950606)
0.536
2
UniProt:Q05397 PTK2
11
p-6Y-PTK2 [cytosol]
(R-HSA-354128)
p-Y397-PTK2 [cytosol]
(R-HSA-354068)
PTK2 [cytosol]
(R-HSA-201621)
PTK2(1-772) [cytosol]
(R-HSA-202827)
PTK2(773-1052) [cytosol]
(R-HSA-202829)
p-5Y-PTK2 [cytosol]
(R-HSA-5218711)
p-5Y,S732-PTK2 [cytosol]
(R-HSA-5229006)
p-6Y,S732-PTK2 [cytosol]
(R-HSA-5218694)
pY-PTK2 [cytosol]
(R-HSA-9632393)
p-Y194,Y397-PTK2 [cytosol]
(R-HSA-8874600)
p-Y194,Y397,Y576,Y577-PTK2 [cytosol]
(R-HSA-8874613)
0.536
3
UniProt:P10276 RARA
3
RARA [nucleoplasm]
(R-HSA-446164)
polySUMO2-K166,K171,K399-RARA [nucleoplasm]
(R-HSA-4341042)
SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm]
(R-HSA-5334830)
0.532
4
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.527
3
UniProt:Q00978 IRF9
2
IRF9 [nucleoplasm]
(R-HSA-913522)
IRF9 [cytosol]
(R-HSA-879183)
0.527
3
UniProt:P0C1C7 W
0.527
2
UniProt:Q997F2 V
0.527
2
UniProt:Q77M19 Q77M19
0.527
4
UniProt:P26664 POLG
0.524
5
UniProt:Q01094 E2F1
2
E2F1 [nucleoplasm]
(R-HSA-68639)
p-E2F1 [nucleoplasm]
(R-HSA-187911)
0.524
2
UniProt:Q4VW77 Q4VW77
0.524
2
IntAct:EBI-10097350 STAT
0.524
2
UniProt:P03255-1
0.508
2
UniProt:Q16531 DDB1
1
DDB1 [nucleoplasm]
(R-HSA-53489)
0.508
2
UniProt:P19793 RXRA
4
RXRA [nucleoplasm]
(R-HSA-381319)
monoSUMO1-K108-RXRA [nucleoplasm]
(R-HSA-4341130)
p-S21-RXRA [nucleoplasm]
(R-HSA-5334811)
RXRA [cytosol]
(R-HSA-9619757)
0.508
2
UniProt:P17181 IFNAR1
2
IFNAR1 [plasma membrane]
(R-HSA-877334)
p-Y466,Y481-IFNAR1 [plasma membrane]
(R-HSA-909675)
0.499
2
UniProt:P48551 IFNAR2
0.499
2
IntAct:EBI-9825772 C-FOS PROMOTER REGION
0.499
3
IntAct:EBI-10097414 FOXP3
0.499
2
UniProt:P11277 SPTB
1
SPTB [cytosol]
(R-HSA-391565)
0.488
2
UniProt:P27958-PRO_0000037576
0.463
4
UniProt:Q9UIV1 CNOT7
1
CNOT7 [cytosol]
(R-HSA-429877)
0.463
2
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