Reactome | GTF2E2 [nucleoplasm]

GTF2E2 [nucleoplasm]

Stable Identifier

R-HSA-65563

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription initiation factor IIE, beta subunit, TFIIE-beta

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P29084 GTF2E2

Gene Names

GTF2E2, TF2E2

Chain

chain:1-291

Reference Genes

BioGPS Gene:2961 GTF2E2

COSMIC (genes):GTF2E2 GTF2E2

CTD Gene:2961 GTF2E2

dbSNP Gene:2961 GTF2E2

ENSEMBL:ENSG00000197265 GTF2E2

HGNC:4651 GTF2E2

KEGG:hsa:2961 GTF2E2

Monarch:2961 GTF2E2

NCBI Gene:2961 GTF2E2

OMIM:189964 GTF2E2

UCSC:P29084 GTF2E2

Reference Transcript

Other Identifiers

11716510_at

17076046

202680_PM_at

202680_at

2672576

2961

3130124

3130125

3130126

3130127

3130129

3130130

3130132

3130133

3130134

3130135

3130136

3130139

3130143

3130144

3130145

37295_at

8150103

A_23_P94118

GE59891

GE769372

GO:0001097

GO:0003677

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005669

GO:0005673

GO:0005829

GO:0006351

GO:0006366

GO:0006367

GO:0016251

GO:0043226

GO:0140223

HMNXSV003042586

ILMN_1664931

PH_hs_0004446

TC08001109.hg

X63469_at

g4504194_3p_at

Participates

as a component of

TFIIE [nucleoplasm] (Homo sapiens)

Inferred To

GTF2E2 [nucleoplasm] (Bos taurus)

GTF2E2 [nucleoplasm] (Canis familiaris)

GTF2E2 [nucleoplasm] (Gallus gallus)

GTF2E2 [nucleoplasm] (Sus scrofa)

gtf2e2 [nucleoplasm] (Danio rerio)

gtf2e2 [nucleoplasm] (Dictyostelium discoideum)

gtf2e2 [nucleoplasm] (Xenopus tropicalis)

Gtf2e2 [nucleoplasm] (Mus musculus)

Gtf2e2 [nucleoplasm] (Rattus norvegicus)

tfa2 [nucleoplasm] (Schizosaccharomyces pombe)

Ghost homologue of GTF2E2 [nucleoplasm] (Plasmodium falciparum)

TfIIEbeta [nucleoplasm] (Drosophila melanogaster)

TFA2 [nucleoplasm] (Saccharomyces cerevisiae)

gtf-2e2 [nucleoplasm] (Caenorhabditis elegans)

Cross References

OpenTargets

ENSG00000197265

ENSEMBL

ENSP00000348168, ENSG00000197265, ENST00000355904

HPA

ENSG00000197265-GTF2E2

GeneCards

GTF2E2

PRO

P29084

Pharos - Targets

P29084

Orphanet

GTF2E2

GlyGen

P29084

PDB

7NVR, 8BYQ, 7NVY, 8S52, 8GXS, 7NVS, 7NVU, 8S51, 7NVZ, 7NVT, 8GXQ, 7EG9, 7EGC, 7EGA, 7EGB, 8BVW, 7LBM, 1D8K, 1D8J, 5IYC, 8WAL, 8WAK, 5IYD, 8WAR, 8WAS, 6O9L, 7NW0, 8WAN, 8WAP, 8S5N, 8WAO, 8WAQ, 5IY6, 5GPY, 7ENA, 7ENC, 5IY9, 8S55, 5IYB, 5IYA, 5IY7, 5IY8

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.556	5
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3
UniProt:Q00341 HDLBP	1	HDLBP [plasma membrane] (R-HSA-8858026)	0.527	2
UniProt:Q9Y490 TLN1	4	TLN1 [extracellular region] (R-HSA-350693) TLN1(434-2541) [cytosol] (R-HSA-9855156) TLN1(1-433) [cytosol] (R-HSA-9855031) TLN1 [cytosol] (R-HSA-350713)	0.527	2
UniProt:P39748 FEN1	1	FEN1 [nucleoplasm] (R-HSA-54745)	0.527	2
UniProt:Q9NPD8 UBE2T	3	UBE2T [nucleoplasm] (R-HSA-420942) MonoUb-K91,K182-UBE2T [nucleoplasm] (R-HSA-6785362) Ub-C86-UBE2T [nucleoplasm] (R-HSA-8864217)	0.527	2
UniProt:O43776 NARS1	1	NARS [cytosol] (R-HSA-379625)	0.527	2
UniProt:P62495 ETF1	3	ETF1 [cytosol] (R-HSA-54433) 4OHK63-ETF1 [cytosol] (R-HSA-9629948) Me-Q185-ETF1 [cytosol] (R-HSA-6800157)	0.527	2
UniProt:Q9Y570 PPME1	1	PPME1 [nucleoplasm] (R-HSA-8857790)	0.527	2
UniProt:P09110 ACAA1	6	ACAA1(1-26) [peroxisomal matrix] (R-HSA-9033534) ACAA1(1-424) [peroxisomal matrix] (R-HSA-9033517) ACAA1(1-424) [cytosol] (R-HSA-9033127) ACAA1 [peroxisomal matrix] (R-HSA-390238) ACAA1 [extracellular region] (R-HSA-6799680) ACAA1 [specific granule lumen] (R-HSA-6799608)	0.527	2
UniProt:Q14691 GINS1	1	GINS1 [nucleoplasm] (R-HSA-176955)	0.527	2
UniProt:P49915 GMPS	1	GMPS [cytosol] (R-HSA-56085)	0.527	2
UniProt:Q15126 PMVK	1	PMVK [cytosol] (R-HSA-191348)	0.527	2
UniProt:P43897 TSFM	1	TSFM [mitochondrial matrix] (R-HSA-5389837)	0.527	2
UniProt:P27144 AK4	1	AK4 [mitochondrial matrix] (R-HSA-6788783)	0.527	2

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