TRAF2 [cytosol]

Stable Identifier
R-HSA-66370
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
TNF receptor associated factor 2, Tumor necrosis factor type 2 receptor associated protein 3
Icon
TRAF2 [cytosol] icon
TRAF2 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q12933 TRAF2
Gene Names
TRAF2, TRAP3
Chain
initiator methionine:, chain:2-501
Reference Genes
BioGPS Gene:7186 TRAF2
COSMIC (genes):TRAF2 TRAF2
CTD Gene:7186 TRAF2
dbSNP Gene:7186 TRAF2
ENSEMBL:ENSG00000127191 TRAF2
ENSEMBL_homo_sapiens_GENE:ENSG00000127191.18 TRAF2
HGNC:12032 TRAF2
KEGG Gene (Homo sapiens):7186 TRAF2
Monarch:7186 TRAF2
NCBI Gene:7186 TRAF2
OMIM:601895 TRAF2
UCSC:Q12933 TRAF2
Reference Transcript
Other Identifiers
11749036_a_at
11754185_a_at
17091444
1746_s_at
204413_PM_at
204413_at
3194905
3194916
3194917
3194918
3194919
3194920
3194928
3194930
3194937
3194943
3194944
3194945
3194946
3194950
3194951
3194952
3194953
3194954
3194955
33784_at
7186
8159476
A_14_P103294
A_23_P169331
A_33_P3424295
A_33_P3803639
GE82592
GO:0000151
GO:0002376
GO:0002637
GO:0002726
GO:0002947
GO:0003824
GO:0004842
GO:0005164
GO:0005174
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005829
GO:0005886
GO:0005938
GO:0006351
GO:0006355
GO:0006915
GO:0007165
GO:0007250
GO:0008270
GO:0008289
GO:0009898
GO:0012501
GO:0012506
GO:0016071
GO:0016567
GO:0016740
GO:0019899
GO:0019901
GO:0019903
GO:0023019
GO:0023052
GO:0030163
GO:0030674
GO:0031435
GO:0031625
GO:0031996
GO:0032743
GO:0032991
GO:0033209
GO:0034351
GO:0034976
GO:0035591
GO:0035631
GO:0036211
GO:0038061
GO:0042802
GO:0042981
GO:0043120
GO:0043123
GO:0043226
GO:0043254
GO:0043507
GO:0044877
GO:0045087
GO:0045121
GO:0046328
GO:0046625
GO:0046872
GO:0048255
GO:0048584
GO:0051091
GO:0051092
GO:0051865
GO:0060090
GO:0065003
GO:0070059
GO:0070534
GO:0071732
GO:0097057
GO:0097300
GO:0097400
GO:0098542
GO:0140096
GO:1903265
GO:1990604
GO:2001238
HMNXSV003054154
ILMN_1691487
PH_hs_0020685
TC09000826.hg
g10863938_3p_at
Participates
as a member of
as a component of
as an input of
Other forms of this molecule
TRAF2 [nucleoplasm]
K63polyUb-TRAF2 [nucleoplasm]
K63polyUb-TRAF2 [cytosol]
PolyUb-TRAF2 [cytosol]
Inferred To
TRAF2 [cytosol] (Bos taurus)
TRAF2 [cytosol] (Canis familiaris)
TRAF2 [cytosol] (Gallus gallus)
TRAF2 [cytosol] (Sus scrofa)
traf2b [cytosol] (Danio rerio)
traf2 [cytosol] (Xenopus tropicalis)
Traf2 [cytosol] (Mus musculus)
Traf2 [cytosol] (Rattus norvegicus)
Cross References
RefSeq
OpenTargets
IntEnz
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
PDB
Interactors (331)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P25942 CD40      0.955 20
 UniProt:Q13490 BIRC2  5 0.951 19
 UniProt:Q15628 TRADD  1 0.942 14
 UniProt:Q12933 TRAF2  5 0.936 12
 UniProt:Q9Y4K3 TRAF6  8 0.905 10
 UniProt:Q9UHD2 TBK1  5 0.893 9
 UniProt:Q13077 TRAF1  3 0.887 14
 UniProt:Q13546 RIPK1  20 0.884 10
 UniProt:Q13489 BIRC3  3 0.865 8
 UniProt:Q12805 EFEMP1  1 0.863 12
 UniProt:P54253 ATX1      0.859 14
 UniProt:Q92844 TANK  2 0.854 10
 UniProt:O95999 BCL10  3 0.85 11
 UniProt:Q96CG3 TIFA  2 0.844 13
 UniProt:P21580 TNFAIP3  1 0.831 10
 UniProt:Q9H8Y8 GORASP2  2 0.83 8
 UniProt:Q9BT49 THAP7      0.83 13
 UniProt:O43741 PRKAB2  2 0.83 8
 UniProt:Q9NZD8 SPG21      0.83 8
 UniProt:P54725 RAD23A  1 0.83 8
 UniProt:Q6FIF0 ZFAND6  1 0.809 8
 UniProt:P46527 CDKN1B  8 0.799 6
 UniProt:P01375 TNF  5 0.788 9
 UniProt:Q15560 TCEA2      0.781 7
 UniProt:Q9H0I2 ENKD1      0.781 7
 UniProt:Q9NRN7 AASDHPPT  1 0.781 7
 UniProt:Q99618 CDCA3      0.781 7
 UniProt:Q96JS3 PGBD1      0.781 7
 UniProt:Q06547 GABPB1      0.781 7
 UniProt:Q92917 GPKOW  1 0.781 7
 UniProt:O76041 NEBL      0.781 7
 UniProt:O75604 USP2  2 0.781 7
 UniProt:Q13526 PIN1  2 0.781 7
 UniProt:Q99558 MAP3K14  5 0.749 9
 UniProt:P19438 TNFRSF1A  2 0.745 5
 UniProt:Q9NVF7 FBX28      0.743 9
 UniProt:Q8TBB1 LNX1  1 0.742 5
 UniProt:O60941 DTNB      0.742 5
 UniProt:Q5T124 UBXN11  1 0.742 5
 UniProt:P48380 RFX3      0.742 5
 UniProt:Q7Z434 MAVS  2 0.742 5
 UniProt:Q05516 ZBTB16  1 0.739 5
 UniProt:Q8TD31-3 CCHCR1      0.718 8
 UniProt:Q5JVL4 EFHC1      0.718 6
 UniProt:Q9BXY8 BEX2      0.718 6
 UniProt:Q9BXF9 TEKT3      0.718 6
 UniProt:Q9BRJ7 TIRR      0.718 6
 UniProt:Q9H0W8 SMG9  1 0.718 6
 UniProt:P57682 KLF3      0.718 6
 UniProt:Q6PF18 MORN3      0.718 6
 UniProt:Q9BRP7 FDXA1      0.718 6
 UniProt:Q0D2K3 RIPP1      0.718 6
 UniProt:Q9BSW7 SYT17      0.718 6
 UniProt:Q9HC52 CBX8  1 0.718 6
 UniProt:Q86YD7 F90A1      0.718 6
 UniProt:Q02930-3 CREB5      0.718 6
 UniProt:Q96IZ5 RBM41      0.718 6
 UniProt:P07947 YES1  2 0.718 6
 UniProt:O60437 PPL  2 0.718 6
 UniProt:Q96NC0 ZMAT2  1 0.718 6
 UniProt:Q99683 MAP3K5  1 0.704 4
 UniProt:Q92956 TNFRSF14  1 0.692 3
 UniProt:O43353 RIPK2  2 0.688 3
 UniProt:P09211 GSTP1  4 0.68 5
 UniProt:P20333 TNFRSF1B  3 0.678 4
 UniProt:P36941 LTBR  1 0.669 4
 UniProt:Q14164 IKBKE  5 0.669 3
 UniProt:Q12815 TROAP      0.666 5
 UniProt:Q8N2X6 EXAS1      0.666 4
 UniProt:Q8TBE0 BAHD1      0.666 4
 UniProt:Q96IX9 A26L1      0.666 4
 UniProt:Q9P2K3 RCOR3      0.666 4
 UniProt:P24278 ZBT25      0.666 4
 UniProt:X5D778 X5D778      0.666 4
 UniProt:Q8N9N5 BANP  1 0.666 4
 UniProt:Q6NX49 ZNF544  1 0.666 4
 UniProt:Q96EK7 FAM120B  1 0.666 4
 UniProt:Q9UKG1 APPL1  1 0.653 3
 UniProt:P63261 ACTG1  3 0.65 3
 UniProt:P00533 EGFR  20 0.635 4
 UniProt:O75460 ERN1  2 0.628 3
 UniProt:O43464 HTRA2  1 0.615 3
 UniProt:P20334  1 0.609 2
 UniProt:P28908 TNFRSF8  1 0.59 2
 UniProt:Q9Y6Q6 TNFRSF11A  1 0.589 2
 UniProt:P09022 Hoxa1  1 0.57 3
 UniProt:B2R8Y4 B2R8Y4      0.556 3
 UniProt:Q96JP2 MY15B      0.556 3
 UniProt:Q5HYW2 NHSL2      0.556 3
 UniProt:P48751 SLC4A3  1 0.556 3
 UniProt:Q8N6N6 NATD1      0.556 3
 UniProt:Q16649 NFIL3  1 0.556 3
 UniProt:Q9UHP6 RSP14      0.556 3
 UniProt:Q92529 SHC3  2 0.556 3
 UniProt:Q01844 EWS      0.556 3
 UniProt:Q8NI38 IKBD      0.556 3
 UniProt:Q6B0K9 HBM      0.556 3
 UniProt:Q5T8A7 PPR26      0.556 3
 UniProt:Q86X59 CQ082      0.556 3
 UniProt:Q8IZU1 FAM9A      0.556 3
 UniProt:Q14119 VEZF1      0.556 3
 UniProt:A0A0S2Z3N6 A0A0S2Z3N6      0.556 3
 UniProt:Q14511-2 NEDD9      0.556 3
 UniProt:P53672 CRBA2      0.556 3
 UniProt:Q8IYS8 BD1L2      0.556 3
 UniProt:Q96HA1-2 POM121      0.556 3
 UniProt:Q9BWG6 SCNM1      0.556 3
 UniProt:Q9NTX7-2 RNF146      0.556 3
 UniProt:P26196 DDX6  1 0.556 3
 UniProt:P51800-3 CLCNKA      0.556 3
 UniProt:Q5T5P2-6 KIAA1217      0.556 3
 UniProt:Q9UJ78-2 Q9UJ782      0.556 3
 UniProt:Q53FD0-2 ZC2HC1C      0.556 3
 UniProt:Q07002 CDK18      0.556 3
 UniProt:Q8N9N2-2 ASCC1      0.556 3
 UniProt:Q14687 GSE1      0.556 3
 UniProt:P55040 GEM  1 0.556 3
 UniProt:P09067 HXB5      0.556 3
 UniProt:Q3SY00 T10IP      0.556 3
 UniProt:P47897 QARS1  2 0.556 3
 UniProt:P49711 CTCF  1 0.556 3
 UniProt:Q92997 DVL3  4 0.556 3
 IntAct:EBI-22620261 CCSB ORF ID      0.556 3
 UniProt:Q16512 PKN1  3 0.556 3
 UniProt:Q2TBE0 CWF19L2  1 0.556 3
 UniProt:Q99633 PRPF18  1 0.556 3
 UniProt:Q9UIF8 BAZ2B      0.556 3
 UniProt:Q8IY51 TIGD4      0.556 3
 UniProt:Q86Y33-5 CDC20B      0.556 3
 UniProt:Q8N6R0 EFNMT      0.556 3
 UniProt:Q3MJ62 ZSC23      0.556 6
 UniProt:Q8WYQ4-2 C22ORF15      0.556 3
 UniProt:Q9Y4B4 ARIP4      0.556 3
 UniProt:Q9BV90 SNRNP25  1 0.556 3
 UniProt:P13682 ZNF35      0.556 3
 UniProt:Q63HK5 TSH3      0.556 3
 UniProt:Q9BRR0 ZKSCAN3  1 0.556 3
 UniProt:Q86UR1-2 NOXA1      0.556 3
 UniProt:O95990-4 FAM107A      0.556 3
 UniProt:Q5T619 ZN648      0.556 3
 UniProt:Q53FD0 ZC21C      0.556 3
 UniProt:P0DTD1-PRO_0000449631 REP      0.556 3
 UniProt:Q4V328 GRAP1      0.556 3
 IntAct:EBI-10178833 4356      0.556 3
 UniProt:P12268 IMPDH2  4 0.556 3
 UniProt:Q9C086 INO80B  1 0.556 3
 UniProt:P41225 SOX3  1 0.556 3
 UniProt:P35227 PCGF2  1 0.556 3
 UniProt:Q9NX65 ZSCAN32  1 0.556 3
 UniProt:Q8N5N6 Q8N5N6      0.556 3
 UniProt:Q8NA54 IQUB      0.556 3
 UniProt:Q9H5Z6-2 FAM124B      0.556 3
 UniProt:Q5T8I9 HENMT1  1 0.556 3
 UniProt:P56279 TCL1A      0.556 3
 UniProt:Q13671 RIN1  1 0.556 3
 UniProt:B4DE54 B4DE54      0.556 3
 UniProt:Q9BVG8 KIFC3      0.556 3
 UniProt:Q4VC44 FWCH1      0.556 3
 UniProt:G2XKQ0 SUMO5      0.556 3
 UniProt:P89055 P89055      0.556 3
 UniProt:O95872 GPAN1      0.556 3
 UniProt:Q8N9N5-2 BANP      0.556 3
 UniProt:O75367 H2AY      0.556 3
 UniProt:Q8WWW0 RASF5      0.556 3
 UniProt:Q8N9N5-7 BANP      0.556 3
 UniProt:Q96MY7 F161B      0.556 3
 UniProt:O95994 AGR2      0.556 3
 UniProt:Q9H788 SH24A      0.556 3
 UniProt:O75808 CAPN15  1 0.556 3
 UniProt:Q9BVG8-5 KIFC3      0.556 3
 UniProt:Q96CV8 Q96CV8      0.556 3
 UniProt:Q8N720 ZNF655  1 0.556 3
 UniProt:Q8TAU3 ZNF417  1 0.556 3
 UniProt:Q92558 WASF1  3 0.556 3
 UniProt:Q7Z4V0 ZN438      0.556 3
 UniProt:Q7L5A3 ATOSB      0.556 3
 UniProt:Q96MN9 ZN488      0.556 3
 UniProt:A0A0S2Z3V1 A0A0S2Z3V1      0.556 3
 UniProt:Q86TN4-2 TRPT1      0.556 3
 UniProt:Q86SE9 PCGF5  1 0.556 3
 UniProt:Q6ZSB9 ZBT49      0.556 3
 UniProt:Q5GFL6 VWA2      0.556 3
 UniProt:Q86VK4 ZN410      0.556 3
 UniProt:Q9BRU9 UTP23      0.556 3
 UniProt:O95863 SNAI1  1 0.556 3
 UniProt:O15273 TCAP  1 0.556 3
 UniProt:Q8IVT4 Q8IVT4      0.556 3
 UniProt:Q8IVT2 MISP      0.556 3
 UniProt:Q9GZU8 PIP30      0.556 3
 UniProt:Q8NEC5 CATSPER1  1 0.556 3
 UniProt:Q53TS8 CTSRT      0.556 3
 UniProt:Q7Z5V6-2 SAXO4      0.556 3
 UniProt:Q17RB8 LONRF1  1 0.556 3
 UniProt:Q9UHB7-2 AFF4      0.556 3
 UniProt:Q6BCY4 CYB5R2  1 0.556 3
 UniProt:Q5T7P8-2 SYT6      0.556 3
 UniProt:Q9Y3D2 MSRB2  1 0.556 3
 UniProt:Q53EP0-3 FNDC3B      0.556 3
 UniProt:Q7Z3I7 ZN572      0.556 3
 UniProt:E9PSE9 E9PSE9      0.556 3
 UniProt:P78317 RNF4  2 0.556 3
 UniProt:Q9HBE1-4 PATZ1      0.556 3
 UniProt:Q96BZ8 LENG1  1 0.556 3
 UniProt:Q6NYC8 PPR18      0.556 3
 UniProt:Q9UBU8-2 MORF4L1      0.556 3
 UniProt:Q7KZS0 Q7KZS0      0.556 3
 UniProt:P29972 AQP1  1 0.556 3
 UniProt:Q86VK4-3 ZNF410      0.556 3
 UniProt:Q9Y5U2 TSSC4      0.556 3
 UniProt:Q8N8B7-2 TCEANC      0.556 3
 UniProt:Q8IV13 CCNJL      0.556 3
 UniProt:Q6BCY4-2 CYB5R2      0.556 3
 IntAct:EBI-22421838 CCSB ORF ID      0.556 3
 UniProt:Q96MM6 HSPA12B  2 0.556 3
 UniProt:Q9Y2J4-4 AMOTL2      0.556 3
 UniProt:O60941-5 DTNB      0.556 3
 UniProt:P63165 SUMO1  11 0.556 3
 UniProt:Q2TAL8 QRIC1      0.556 3
 UniProt:Q8WTU0 DDI1      0.556 3
 UniProt:Q9Y6H1 CHCHD2  2 0.556 3
 UniProt:Q6X4W1-2 NSMF      0.556 3
 UniProt:O15353 FOXN1      0.556 3
 UniProt:Q9Y4C2-2 TCAF1      0.556 3
 UniProt:Q96S90 LYSM1      0.556 3
 UniProt:Q2KHT4 GSG1      0.556 3
 UniProt:P15622-3 ZNF250      0.556 3
 UniProt:Q8IXW0 LMTD2      0.556 3
 UniProt:Q8NHY3 GA2L2      0.556 3
 UniProt:Q96PC2 IP6K3  1 0.556 3
 UniProt:Q9BUI4 POLR3C  2 0.556 3
 UniProt:P57055 DSCR6      0.556 3
 UniProt:Q3B820 F161A      0.556 3
 UniProt:Q13064 MKRN3      0.556 3
 UniProt:Q9NRE2 TSH2      0.556 3
 UniProt:A0A0S2Z6P0 A0A0S2Z6P0      0.556 3
 UniProt:Q96NU1 SAM11      0.556 3
 UniProt:Q8IWZ5 TRI42      0.556 3
 UniProt:Q32MK9 Q32MK9      0.556 3
 UniProt:Q9HC98-4 NEK6      0.556 3
 UniProt:Q9Y247 FA50B      0.556 3
 UniProt:Q9UN79 SOX13  1 0.556 3
 UniProt:Q4G0R1 Q4G0R1      0.556 3
 UniProt:Q6GPH6-2 ITPRIPL1      0.556 3
 UniProt:O43708 GSTZ1  2 0.556 3
 UniProt:A0A384ME25 A0A384ME25      0.556 3
 UniProt:Q86Y33 CD20B      0.556 3
 UniProt:P00540 MOS      0.556 3
 UniProt:Q5T124-6 UBXN11      0.556 3
 UniProt:P35711-4 SOX5      0.556 3
 UniProt:Q5TAP6 UTP14C  1 0.556 3
 UniProt:Q16656-4 NRF1      0.556 3
 UniProt:Q96MP5 ZSWM3      0.556 3
 IntAct:EBI-10227439 55083      0.556 3
 UniProt:P41182 BCL6  1 0.556 3
 UniProt:Q8N9N2 ASCC1  1 0.556 3
 UniProt:Q8IYX8-2 CEP57L1      0.556 3
 UniProt:O15169 AXIN1  11 0.556 3
 UniProt:Q6ZS27-3 ZNF662      0.556 3
 UniProt:O75928-2 PIAS2  1 0.556 3
 UniProt:Q496Y0 LONF3      0.556 3
 UniProt:Q16543 CDC37  1 0.556 3
 UniProt:O00463 TRAF5      0.556 5
 UniProt:Q14142 TRIM14  1 0.556 3
 UniProt:Q9NVL8 FAME      0.556 3
 UniProt:Q9NTX7 RNF146  1 0.556 3
 UniProt:Q63ZY3 KANK2      0.556 3
 UniProt:Q5W5X9-3 TTC23      0.556 3
 UniProt:P10599 TXN  4 0.556 3