Reactome | XAB2 [nucleoplasm]

XAB2 [nucleoplasm]

Stable Identifier

R-HSA-67411

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

XPA-binding protein 2, HCNP protein, PP3898

Locations in the PathwayBrowser for interactor UniProt:Q03468 ERCC6

Expand all

External Reference Information

External Reference

UniProt:Q9HCS7 XAB2

Gene Names

XAB2, HCNP, KIAA1177, SYF1, PP3898

Chain

chain:1-855

Reference Genes

BioGPS Gene:56949 XAB2

COSMIC (genes):XAB2 XAB2

CTD Gene:56949 XAB2

dbSNP Gene:56949 XAB2

ENSEMBL:ENSG00000076924 XAB2

HGNC:14089 XAB2

KEGG Gene (Homo sapiens):56949 XAB2

Monarch:56949 XAB2

NCBI Gene:56949 XAB2

OMIM:610850 XAB2

UCSC:Q9HCS7 XAB2

Reference Transcript

RefSeq:NM_020196.2 XAB2

Other Identifiers

0002260142

11757909_a_at

16867948

218110_at

3848443

3848444

3848446

3848447

3848448

3848450

3848451

3848453

3848455

3848456

3848458

3848461

3848464

3848465

3848466

3848469

3848471

3848473

3848476

3848477

3848478

3848479

47620_at

56949

8033392

A_23_P142013

A_24_P2093

GE53813

GO:0000349

GO:0000398

GO:0000974

GO:0001824

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0006259

GO:0006281

GO:0006283

GO:0006351

GO:0006396

GO:0006397

GO:0006950

GO:0006974

GO:0008150

GO:0008380

GO:0009058

GO:0009790

GO:0016020

GO:0021987

GO:0022607

GO:0022618

GO:0032991

GO:0034641

GO:0043226

GO:0043231

GO:0048856

GO:0065003

GO:0071007

GO:0071013

GO:0071014

HMNXSV003053797

ILMN_1771057

PH_hs_0001015

TC19001114.hg

g9910259_3p_at

Participates

as a component of

as an input of

Formation of the Spliceosomal B Complex (Homo sapiens)

Inferred To

fand [nucleoplasm] (Drosophila melanogaster)

syf-1 [nucleoplasm] (Caenorhabditis elegans)

SYF1 [nucleoplasm] (Saccharomyces cerevisiae)

Xab2 [nucleoplasm] (Mus musculus)

Xab2 [nucleoplasm] (Rattus norvegicus)

xab2 [nucleoplasm] (Danio rerio)

xab2 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of XAB2 [nucleoplasm] (Gallus gallus)

XAB2 [nucleoplasm] (Canis familiaris)

XAB2 [nucleoplasm] (Sus scrofa)

XAB2 [nucleoplasm] (Xenopus tropicalis)

cwf3 [nucleoplasm] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_064581.2

OpenTargets

ENSG00000076924

GeneCards

Q9HCS7

HPA

ENSG00000076924-XAB2

Ensembl

ENST00000358368, ENSG00000076924, ENSP00000351137

PRO

Q9HCS7

Pharos - Targets

Q9HCS7

GlyGen

Q9HCS7

PDB

5Z56, 6ID0, 6QDV, 7ABI, 6ID1, 7A5P, 6FF7, 5Z57, 5XJC, 6ICZ, 5MQF, 5YZG

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UNP9 PPIE	4	PPIE [secretory granule lumen] (R-HSA-6801369) PPIE [extracellular region] (R-HSA-6806493) PPIE [ficolin-1-rich granule lumen] (R-HSA-6801393) PPIE [nucleoplasm] (R-HSA-6781959)	0.882	12
UniProt:O60306 AQR	1	AQR [nucleoplasm] (R-HSA-6781960)	0.737	6
UniProt:Q9ULR0 ISY1	1	ISY1 [nucleoplasm] (R-HSA-6781963)	0.703	7
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.59	2
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q13216 ERCC8	1	ERCC8 [nucleoplasm] (R-HSA-52835)	0.524	3
UniProt:P23025 XPA	1	XPA [nucleoplasm] (R-HSA-67437)	0.508	2
UniProt:O60231 DHX16	1	DHX16 [nucleoplasm] (R-HSA-8850837)	0.508	2
UniProt:Q13435 SF3B2	1	SF3B2 [nucleoplasm] (R-HSA-71971)	0.508	2
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.508	2
UniProt:Q13123 RED			0.508	2
UniProt:Q03468 ERCC6	2	Ub-ERCC6 [nucleoplasm] (R-HSA-6781853) ERCC6 [nucleoplasm] (R-HSA-54429)	0.499	2

Cite Us!