Reactome | YOD1 [cytosol]

YOD1 [cytosol]

Stable Identifier

R-HSA-6781909

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ubiquitin thioesterase OTU1, OTU1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5VVQ6 YOD1

Gene Names

YOD1, DUBA8, HIN7, OTUD2, PRO0907

Chain

chain:1-348

Reference Genes

BioGPS Gene:55432 YOD1

COSMIC (genes):YOD1 YOD1

CTD Gene:55432 YOD1

dbSNP Gene:55432 YOD1

ENSEMBL:ENSG00000180667 YOD1

ENSEMBL_homo_sapiens_GENE:ENSG00000180667.11 YOD1

HGNC:25035 YOD1

KEGG Gene (Homo sapiens):55432 YOD1

Monarch:55432 YOD1

NCBI Gene:55432 YOD1

OMIM:612023 YOD1

UCSC:Q5VVQ6 YOD1

Reference Transcript

Other Identifiers

11724635_at

16698764

16698766

215150_PM_at

215150_at

227309_PM_at

227309_at

2453088

2453090

2453091

2453092

2453093

2453095

2453096

2453097

2453098

2453099

2453100

3197913

52762_at

55432

7923965

7923967

A_24_P32790

A_32_P178945

A_32_P69803

GO:0003824

GO:0004843

GO:0005515

GO:0005737

GO:0005829

GO:0006508

GO:0006886

GO:0006914

GO:0006986

GO:0008233

GO:0008234

GO:0016236

GO:0016787

GO:0023052

GO:0030163

GO:0030433

GO:0030968

GO:0031625

GO:0035523

GO:0035871

GO:0036211

GO:0046872

GO:0061578

GO:0070536

GO:0071108

GO:0101005

GO:0140096

GO:1904153

GO:1990167

GO:1990168

GO:1990380

HMNXSV003021873

HMNXSV003053413

Hs.163001.1.A1_3p_at

Hs.8688.0.A1_3p_at

ILMN_1678919

ILMN_2138856

PH_hs_0018934

TC01003772.hg

TC01003773.hg

Participates

as a component of

YOD1:VCP [cytosol] (Homo sapiens)

as an input of

YOD1 binds VCP (Homo sapiens)

Inferred To

YOD1 [cytosol] (Bos taurus)

YOD1 [cytosol] (Canis familiaris)

YOD1 [cytosol] (Danio rerio)

YOD1 [cytosol] (Dictyostelium discoideum)

YOD1 [cytosol] (Drosophila melanogaster)

YOD1 [cytosol] (Gallus gallus)

YOD1 [cytosol] (Mus musculus)

YOD1 [cytosol] (Rattus norvegicus)

YOD1 [cytosol] (Saccharomyces cerevisiae)

YOD1 [cytosol] (Schizosaccharomyces pombe)

YOD1 [cytosol] (Sus scrofa)

yod1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_061036.3, NP_001263249.1

OpenTargets

ENSG00000180667

HPA

ENSG00000180667-YOD1

GeneCards

Q5VVQ6

Ensembl

ENST00000315927, ENSP00000326813, ENST00000367084, ENSG00000180667, ENSP00000356051

PRO

Q5VVQ6

Pharos - Targets

Q5VVQ6

PDB

4BOQ, 4BOS, 4BOZ

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NPE2 NGRN			0.556	3
UniProt:Q8N0X7 SPART			0.556	3
UniProt:Q9NU63-3 ZFP57			0.556	3
UniProt:Q99942 RNF5	1	RNF5 [endoplasmic reticulum membrane] (R-HSA-975990)	0.556	3
UniProt:Q9NRQ2 PLS4			0.556	3
UniProt:Q9BZV1 UBXN6			0.556	3
UniProt:Q9Y4K3 TRAF6	8	K48polyUb-TRAF6 [cytosol] (R-HSA-6783233) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) TRAF6 [endosome membrane] (R-HSA-450272) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955)	0.556	5
UniProt:P55072 VCP	8	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) VCP [nucleoplasm] (R-HSA-5643745) VCP [secretory granule lumen] (R-HSA-6801039) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [extracellular region] (R-HSA-6806191) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [cytosol] (R-HSA-1181251)	0.556	3
UniProt:Q9UHC7 MKRN1	2	MKRN1 [cytosol] (R-HSA-976042) p-S109-MKRN1 [cytosol] (R-HSA-8948758)	0.556	5
UniProt:O14818 PSMA7	2	PSMA7 [nucleoplasm] (R-HSA-174351) PSMA7 [cytosol] (R-HSA-68736)	0.556	5
UniProt:Q9NWF9 RNF216	1	RNF216 [cytosol] (R-HSA-936043)	0.556	3
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130)	0.556	3
UniProt:Q05BL1 Q05BL1			0.556	3
UniProt:Q9BZR9 TRIM8	1	TRIM8 [cytosol] (R-HSA-5624332)	0.556	3
UniProt:Q15038 DAZP2			0.556	7
UniProt:Q9Y458 TBX22			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:Q92567-2 FAM168A			0.556	5
UniProt:Q96CS7 PKHB2			0.556	5
UniProt:Q96D03 DDT4L			0.556	3
UniProt:P35250-2 RFC2			0.556	3
UniProt:P25791-3 LMO2			0.556	3

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