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Ub-HIST1H2AB [nucleoplasm]
Stable Identifier
R-HSA-6782483
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
HIST1H2AB
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Metalloprotease DUBs (Homo sapiens)
MYSM1 deubiquitinates Histone H2A (Homo sapiens)
MYSM1:EP300:KAT2B:Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AB [nucleoplasm] (Homo sapiens)
UCH proteinases (Homo sapiens)
Histone H2A is dubiquitinated by the PR-DUB complex (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AB [nucleoplasm] (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP16,USP21 deubiquitinate Histone H2A (Homo sapiens)
USP16,USP21:Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AB [nucleoplasm] (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
Ub-histone H2A [nucleoplasm] (Homo sapiens)
Ub-histone HIST1 H2A [nucleoplasm] (Homo sapiens)
Ub-HIST1H2AB [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P04908 HIST1H2AB
Gene Names
HIST1H2AB, H2AFM, HIST1H2AE, H2AFA
Chain
initiator methionine:1, chain:2-130
Reference Genes
BioGPS Gene:3012 HIST1H2AB
BioGPS Gene:8335 HIST1H2AB
COSMIC (genes):HIST1H2AB HIST1H2AB
CTD Gene:3012 HIST1H2AB
CTD Gene:8335 HIST1H2AB
dbSNP Gene:3012 HIST1H2AB
dbSNP Gene:8335 HIST1H2AB
ENSEMBL:ENSG00000277075 HIST1H2AE
ENSEMBL:ENSG00000278463 HIST1H2AB
HGNC:4724 HIST1H2AB
HGNC:4734 HIST1H2AB
KEGG Gene (Homo sapiens):3012 HIST1H2AB
KEGG Gene (Homo sapiens):8335 HIST1H2AB
Monarch:3012 HIST1H2AB
Monarch:8335 HIST1H2AB
NCBI Gene:3012 HIST1H2AB
NCBI Gene:8335 HIST1H2AB
OMIM:602786 HIST1H2AB
OMIM:602795 HIST1H2AB
Reference Transcript
RefSeq:NM_021052.2 HIST1H2AB
RefSeq:NM_003513.2 HIST1H2AB
Other Identifiers
0005130670
0006020338
11731693_at
11731694_s_at
11741215_at
12242
17005589
17016366
208569_at
214469_at
2899224
2899225
2899226
2946220
2946221
2946222
2946223
2946224
2CV5
2RVQ
3012
35127_at
3A6N
3AFA
3AN2
3AV1
3AV2
3AYW
3AZE
3AZF
3AZG
3AZH
3AZI
3AZJ
3AZK
3AZL
3AZM
3AZN
3W96
3W97
3W98
3W99
3WKJ
3WTP
3X1S
3X1V
41189
4YM5
4YM6
4Z5T
5AV5
5AV6
5AV8
5AV9
5AVB
5AVC
5AY8
5B0Y
5B0Z
5B24
5B2I
5B2J
5B31
5B32
5B40
5CPI
5CPJ
5CPK
5GSE
5GTC
5GXQ
5JRG
5X7X
5XF3
5XF4
5XF5
5Y0C
5Y0D
6A5L
6A5O
6A5P
6A5R
6A5T
6A5U
6A5V
6BUZ
6HKT
6HTS
8117408
8124391
8335
A_14_P115530
A_23_P59045
A_24_P223384
AAA63191
AAH93836
AAH93862
AAI25141
AAN59964
AAN59967
AK311785
AK311824
AL031777
AY131983
AY131986
BAG34728
BAG34766
BC093836
BC093862
BC125140
CAA24951
CAB012242
CAB06036
CCDS4574
CCDS4595
CH471087
EAW55512
EAW55546
ENSG00000277075
ENSG00000278463
ENSP00000303373
ENSP00000483842
ENST00000303910
ENST00000303910.4
ENST00000615868
ENST00000615868.1
EntrezGene:3012
EntrezGene:8335
EntrezGene:HIST1H2AB
EntrezGene:HIST1H2AE
g4504246_3p_at
GE504811
GO:0000228
GO:0000786
GO:0000790
GO:0003674
GO:0003677
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005694
GO:0006325
GO:0008150
GO:0008283
GO:0008285
GO:0032991
GO:0043226
GO:0046982
GO:0051276
GO:0070062
HGNC:4724
HGNC:4734
HIST1H2AB
HIST1H2AB-201
HIST1H2AE
HIST1H2AE-201
HPA041189
Hs.121017.0.S1_3p_at
ILMN_1753524
ILMN_1756849
IPR002119
IPR007125
IPR009072
IPR032454
IPR032458
M60752
M60752_at
MIM:602786
MIM:602795
NM_003513
NM_021052
NP_003504
NP_066390
PF00125
PF16211
PH_hs_0013174
PH_hs_0032313
PR00620
Q08AJ9
SM00414
TC06000173.hg
TC06001343.hg
UPI00000007AF
X00089
Z83741
Z83741_at
Participant Of
hasMember
Ub-histone HIST1 H2A [nucleoplasm]
Other forms of this molecule
HIST1H2AB [extracellular region]
K63polyUb-HIST1H2AB [nucleoplasm]
Ack6-HIST1H2AB [nucleoplasm]
Ack-HIST1H2AB [nucleoplasm]
Me2aR30-HIST1H2AB [nucleoplasm]
MeR30-HIST1H2AB [nucleoplasm]
Me2aR4-HIST1H2AB [nucleoplasm]
MeR4-HIST1H2AB [nucleoplasm]
Me2sR4-HIST1H2AB [nucleoplasm]
Me2aR12-HIST1H2AB [nucleoplasm]
MeR12-HIST1H2AB [nucleoplasm]
HIST1H2AB [nucleoplasm]
Inferred To
Homologues of Ub-HIST3H2A [nucleoplasm] (Xenopus tropicalis)
Ub-HIST1H2AB [nucleoplasm] (Bos taurus)
Ub-HIST1H2AB [nucleoplasm] (Canis familiaris)
Ub-HIST1H2AB [nucleoplasm] (Mus musculus)
Ub-HIST1H2AB [nucleoplasm] (Rattus norvegicus)
Ub-HIST1H2AB [nucleoplasm] (Sus scrofa)
Homologues of Ub-HIST1H2AB [nucleoplasm] (Mus musculus)
Ub-HIST3H2A [nucleoplasm] (Caenorhabditis elegans)
Ub-HIST3H2A [nucleoplasm] (Danio rerio)
Ub-HIST3H2A [nucleoplasm] (Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine at 120
Coordinate
120
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_003504.2
,
NP_066390.1
OpenTargets
ENSG00000278463
GeneCards
P04908
PRO
P04908
HMDB Protein
HMDBP07727
PDB
5Z23
,
5AVB
,
5JRG
,
3WKJ
,
6J51
,
3X1V
,
5AVC
,
6INQ
,
6J4Z
,
3AZM
,
3W96
,
5GXQ
,
3W98
,
6J50
,
3X1S
,
6J4Y
,
3A6N
,
5B24
,
6BUZ
,
4YM5
,
6J4X
,
3AZK
,
5GTC
,
5AV8
,
5CPK
,
6HTS
,
3WTP
,
5XF5
,
5AY8
,
6IR9
,
6J4W
,
5X7X
,
6O1D
,
3AZJ
,
5XF4
,
3AZH
,
2CV5
,
5B40
,
5B0Z
,
5B0Y
,
6HKT
,
3AZI
,
3AZF
,
6A5U
,
2RVQ
,
3W99
,
5GSE
,
3AZG
,
6A5T
,
6E0P
,
3AZN
,
3W97
,
6A5R
,
4Z5T
,
5B32
,
4YM6
,
3AZE
,
3AZL
,
6E0C
,
5AV9
,
5ZBX
,
5B31
,
6A5P
,
5AV5
,
6A5O
,
3AFA
,
5CPJ
,
3AYW
,
5AV6
,
5B2J
,
3AN2
,
5CPI
,
5B2I
,
5Y0D
,
5XF3
,
6A5L
,
3AV2
,
5Y0C
,
3AV1
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62805 HIST1H4A
19
SUMO3-HIST1H4 [nucleoplasm]
(R-HSA-4570531)
HIST1H4A [extracellular region]
(R-HSA-977569)
SUMO1-HIST1H4 [nucleoplasm]
(R-HSA-4570518)
4xAcK-HIST1H4A [nucleoplasm]
(R-HSA-427390)
AcK5,12-HIST1H4A [nucleoplasm]
(R-HSA-212078)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-427469)
AcK13-HIST1H4 [nucleoplasm]
(R-HSA-4568744)
AcK6-HIST1H4 [nucleoplasm]
(R-HSA-4568748)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-4568749)
AcK9-HIST1H4 [nucleoplasm]
(R-HSA-4568758)
Me2aR4-HIST1H4 [nucleoplasm]
(R-HSA-5229015)
Me2sR4-HIST1H4 [nucleoplasm]
(R-HSA-4754243)
MeR4-HIST1H4 [nucleoplasm]
(R-HSA-4754240)
Me3K21-HIST1H4 [nucleoplasm]
(R-HSA-5651656)
MeK21-HIST1H4 [nucleoplasm]
(R-HSA-5423110)
AcK-HIST1H4 [nucleoplasm]
(R-HSA-3451124)
MeK-HIST1H4A [nucleoplasm]
(R-HSA-2172676)
HIST1H4 [nucleoplasm]
(R-HSA-181902)
Me2K21-HIST1H4 [nucleoplasm]
(R-HSA-5651652)
0.835
11
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