Reactome | IL33 [nucleoplasm]

IL33 [nucleoplasm]

Stable Identifier

R-HSA-6783145

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Interleukin-33, IL33_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - Ub-specific processing proteases (Homo sapiens)
      - USP21 deubiquitinates GATA3,IL33 (Homo sapiens)
        
        USP21:GATA3,IL33 [nucleoplasm] (Homo sapiens)
        
        GATA3,IL33 [nucleoplasm] (Homo sapiens)
        
        IL33 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O95760 IL33

Gene Names

IL33, C9orf26, IL1F11, NFHEV

Chain

chain:1-270, propeptide:1-94, chain:95-270, chain:99-270, chain:109-270

Reference Genes

BioGPS Gene:90865 IL33

COSMIC (genes):IL33 IL33

CTD Gene:90865 IL33

dbSNP Gene:90865 IL33

ENSEMBL:ENSG00000137033 IL33

HGNC:16028 IL33

KEGG Gene (Homo sapiens):90865 IL33

Monarch:90865 IL33

NCBI Gene:90865 IL33

OMIM:608678 IL33

UCSC:O95760 IL33

Reference Transcript

Other Identifiers

0002680292

11743858_at

11743859_x_at

11751426_a_at

17083433

209821_at

3161341

3161351

3161354

3161355

3161356

3161358

3161359

3161360

3161361

3161362

3161363

35333_r_at

55630_f_at

8154295

90865

A_23_P31945

GE61968

GO:0000122

GO:0000228

GO:0001819

GO:0002112

GO:0002281

GO:0002282

GO:0002376

GO:0002686

GO:0002826

GO:0002830

GO:0003674

GO:0005125

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005720

GO:0005737

GO:0006464

GO:0006810

GO:0006950

GO:0007165

GO:0007267

GO:0008150

GO:0008219

GO:0008283

GO:0009056

GO:0009058

GO:0010186

GO:0010628

GO:0015031

GO:0016579

GO:0030133

GO:0030154

GO:0031410

GO:0032436

GO:0032689

GO:0032736

GO:0032753

GO:0032754

GO:0032755

GO:0034641

GO:0038172

GO:0040011

GO:0042535

GO:0043032

GO:0043226

GO:0045345

GO:0045348

GO:0045944

GO:0048856

GO:0048870

GO:0050729

GO:0051024

GO:0051025

GO:0051607

GO:0051770

GO:0061518

GO:0090197

GO:0097191

GO:0120042

GO:0150078

GO:0150142

GO:0150145

GO:1904469

ILMN_1809099

ILMN_2052924

PH_hs_0032760

TC09000045.hg

g4520327_3p_at

Participant Of

hasMember

GATA3,IL33 [nucleoplasm]

Other forms of this molecule

IL33 [extracellular region]

PolyUb-IL33 [nucleoplasm]

Inferred To

IL33 [nucleoplasm] (Sus scrofa)

Il33 [nucleoplasm] (Mus musculus)

Il33 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001300973.1, NP_001300977.1, NP_001300975.1, NP_001186569.1, NP_001186570.1, NP_001300976.1, NP_001300974.1, NP_254274.1

OpenTargets

ENSG00000137033

GeneCards

O95760

HPA

ENSG00000137033-IL33

Ensembl

ENSG00000137033, ENST00000456383, ENST00000417746, ENST00000381434, ENSP00000414238, ENSP00000394039, ENST00000611532, ENSP00000370842, ENSP00000478858

PRO

O95760

PDB

2KLL, 4KC3

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0C0S8 H2AC11	11	Ub-HIST1H2AG [nucleoplasm] (R-HSA-6782508) K63polyUb-HIST1H2AG [nucleoplasm] (R-HSA-6783237) Ack6-HIST1H2AG [nucleoplasm] (R-HSA-4568595) Ack-HIST1H2AG [nucleoplasm] (R-HSA-4551311) Me2aR30-HIST1H2AG [nucleoplasm] (R-HSA-5244582) MeR30-HIST1H2AG [nucleoplasm] (R-HSA-5244560) Me2aR4-HIST1H2AG [nucleoplasm] (R-HSA-5244587) MeR4-HIST1H2AG [nucleoplasm] (R-HSA-5244623) Me2aR12-HIST1H2AG [nucleoplasm] (R-HSA-5229305) MeR12-HIST1H2AG [nucleoplasm] (R-HSA-5229206) HIST1H2AG [nucleoplasm] (R-HSA-212084)	0.499	3