OTUB1,(OTUB2) binds TP53, UBE2D1, ESR1

Stable Identifier
R-HSA-6783238
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

OTUB1 (and OTUB2) can bind the nuclear proteins MDM2 cognate E2 UBE2D1 (Sun et al. 2012), and ESR1 (Stanisic et al. 2009). OTUB1 has DUB activity but mainly acts by suppressing ubiquitin-conjugating E2 enzymes, independently of its catalytic activity (Sun & Dai 2014).

Participants
Participant Of
Orthologous Events